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Metrizoic acid

Metrizoic acid Structure
Metrizoic acid
  • CAS No.1949-45-7
  • Chemical Name:Metrizoic acid
  • CBNumber:CB1775662
  • Molecular Formula:C12H11I3N2O4
  • Formula Weight:627.94
  • MOL File:1949-45-7.mol
Metrizoic acid Property
Safety
  • Risk Statements  :36/37/38
  • Safety Statements  :26-36/37/39
  • RTECS  :DG0887300
  • HS Code  :2924.29.7790
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H335-H319
  • Precautionary statements P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Metrizoic acid Price More Price(2)
  • Brand: TCI Chemicals (India)
  • Product number: M1363
  • Product name : Metrizoic Acid
  • Purity: 
  • Packaging: 5G
  • Price: ₹3100
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: M1363
  • Product name : Metrizoic Acid
  • Purity: 
  • Packaging: 25G
  • Price: ₹7000
  • Updated: 2022/05/26
  • Buy: Buy

Metrizoic acid Chemical Properties,Usage,Production

  • Originator Isopaque,Winthrop,France,1973
  • Uses Diagnosis aid (radiopaque medium).
  • Definition ChEBI: Metrizoic acid is a monocarboxylic acid. It has a role as a radioopaque medium.
  • Manufacturing Process 3,5-Diacetamido-2,4,6-triiodobenzoic acid (diatrizoic acid) (see Diatrizoate entry for synthesis) (10 g) is suspended in water (10 ml), 5 N potassium hydroxide (4.3 equivalent) is added and the mixture cooled to about 15°C. Dimethyl sulfate (0.5 equivalent) dissolved in an equal volume of acetone is added drop by drop while stirring. After the reaction mixture has been stirred for about 1 hour hydrochloric acid (1:1) is added, with stirring to pH about 0.5. The precipitate is filtered, washed and suspended moist in 4 parts of water, concentrated ammonia is added to pH about 7 and the ammonium salt solution is isomerized at 90°C to 100°C for about one-half hour whereafter additional ammonia is added to pH about 9 followed by solid ammonium chloride (about 10% weight/volume) and the solution stirred overnight and the excess of 3,5-diacetamide-2,4,6-triiodobenzoic acid recovered as ammonium salt on the filter. The filtrate is precipitated by means of hydrochloric acid (1:1 ) at pH about 0.5 and the N-methyl-3,5-diacetamido- 2,4,6-triiodobenzoic acid collected on a filter, washed and dried.
  • Therapeutic Function Diagnostic aid (radiopaque medium)
Metrizoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Metrizoic acid Suppliers
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Metrizoic acid Spectrum
1949-45-7, Metrizoic acidRelated Search:
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Diagnostic
  • Aromatics
  • Amines
  • 抑制剂
  • C12H11I3N2O4
  • 化合物 T16067
  • 3-乙酰氨基-5-(N-甲基乙酰胺)-2,4,6-三碘苯甲酸
  • 甲泛影酸
  • 3-乙酰氨基-5-[乙酰(甲基)氨基]-2,4,6-三碘苯甲酸
  • 1949-45-7
  • Metrizoic acid USP/EP/BP
  • Benzoic acid, 3-(acetylamino)-5-(acetylmethylamino)-2,4,6-triiodo-
  • MetrizoicAcid&gt
  • 3-Acetamido-2,4,6-triiodo-5-(N-methylacetamido)
  • 3,5-DiacetaMido-N-Methyl-2,4,6-triiodobenzoic Acid
  • 3-acetamido-5-[ethanoyl(methyl)amino]-2,4,6-triiodo-benzoic acid
  • 3-acetamido-5-[acetyl(methyl)amino]-2,4,6-triiodo-benzoic acid
  • 3-acetamido-5-[acetyl(methyl)amino]-2,4,6-triiodobenzoic acid
  • Triosil-280
  • 3-Acetylamino-5-(N-methylacetylamino)-2,4,6-triiodobenzoic acid
  • Metrizoic
  • 3-(Acetylamino)-5-[acetyl methyl-amino)2,4,6-triiodobenzoic acid
  • 3-acetamido-2,4,6-triiodo-5-N-methylacetamidobenzoic acid
  • metrizoate
  • 3-acetamido-2,4,6-triiodo-5-(n-methylacetamido)-benzoicaci
  • 3-(acetylamino)-5-(acetylmethylamino)-2,4,6-triiodo-benzoicaci
  • 3-ACETAMIDO-5-(N-METHYLACETAMIDO)-2,4,6-TRIIODOBENZOIC ACID
  • METRIZOIC ACID

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