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SODIUM CARBONATE, MONOHYDRATE

CAS No.5968-11-6
Chemical Name:SODIUM CARBONATE, MONOHYDRATE
CBNumber:CB1704053
Molecular Formula:CH5NaO4
Formula Weight:104.04
MOL File:5968-11-6.mol

SODIUM CARBONATE, MONOHYDRATE Property

Melting point 851 °C(lit.)
Boiling point 1600 °C
Density 2.53
storage temp. Store at RT.
solubility H₂O: 1 M at 20 °C, clear, colorless
form Powder/Solid
Specific Gravity 2.25
color White
PH 11-12 (25°C, 50g/L in H2O)
Water Solubility Soluble in water. Insoluble in alcoholSoluble in water and glycerol. Insoluble in alcohol, acetone, alkyl acetates,benzonitrile and liquid ammonia.
Sensitive Hygroscopic
Merck 14,8596
Dielectric constant 3.0（Ambient）
Stability Stable. Incompatible with strong acids, aluminium, fluorine, lithium, phosphorus oxides.
LogP -0.809 (est)
CAS DataBase Reference 5968-11-6(CAS DataBase Reference)
FDA UNII 2A1Q1Q3557
EPA Substance Registry System Sodium carbonate, monohydrate (5968-11-6)
UNSPSC Code 12352302
NACRES NA.55

Safety

Hazard Codes :Xi
Risk Statements :36
Safety Statements :26-22
WGK Germany :1
RTECS :VZ4050000
F :3
TSCA :Yes
HS Code :28362000

NFPA 704:

	0
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H319
Precautionary statements P264-P280-P305+P351+P338-P337+P313

SODIUM CARBONATE, MONOHYDRATE Price More Price(17)

Brand: Sigma-Aldrich(India)
Product number: S4132
Product name : Sodium carbonate monohydrate
Purity: ReagentPlus?, ≥99.5%
Packaging: 500G
Price: ₹5683.13
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: 230952
Product name : Sodium carbonate monohydrate
Purity: ACS reagent, ≥99.5%
Packaging: 100G
Price: ₹4243.4
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: S4132
Product name : Sodium carbonate monohydrate
Purity: ReagentPlus?, ≥99.5%
Packaging: 1KG
Price: ₹8281.13
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 230952
Product name : Sodium carbonate monohydrate
Purity: ACS reagent, ≥99.5%
Packaging: 500G
Price: ₹7555.85
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 230952
Product name : Sodium carbonate monohydrate
Purity: ACS reagent, ≥99.5%
Packaging: 2.5KG
Price: ₹11647.7
Updated: 2022/06/14
Buy: Buy

SODIUM CARBONATE, MONOHYDRATE Chemical Properties,Usage,Production

Chemical Properties Sodium carbonate is a white, almost white, or colorless inorganic salt, produced as crystalline powder or granules. It is hygroscopic and odorless with an alkaline taste.
Chemical Properties white powder
Uses Buffer component, may be used for the removal of peripheral membrane proteins.
Uses Buffers; pH adjustment.
Uses Sodium Carbonate Monohydrate can be used for sterilization or virus inactivating agent composition.
Production Methods Sodium carbonate is produced by the ammonia-soda process, also known as the Solvay process.
Pharmaceutical Applications Sodium carbonate is used as an alkalizing agent in injectable, ophthalmic, oral, and rectal formulations. In effervescent tablets or granules, sodium carbonate is used in combination with an acid, typically citric acid or tartaric acid. When the tablets or granules come into contact with water, an acid– base reaction occurs in which carbon dioxide gas is produced and the product disintegrates. Raw materials with low moisture contents are required to prevent the early triggering of the effervescent reaction.
As an alkalizing agent, concentrations of sodium carbonate between 2% and 5% w/w are used in compressed tablet formulations. As an effervescent agent, concentrations of sodium carbonate up to 10% w/w can be used.
Therapeutically, sodium carbonate is also used as an oral antacid.
Industrial uses Soda ash is the name of various grades of sodium carbonate (Na2CO3). A large portion of soda ash is manufactured via the Solvay process, based on the following reaction:
NH₃+ CO₂ + H₂O → NH₄HCO₃
NaCl + NH₄HCO₃→ NaHCO₃ + NH₄Cl
2NaHCO₃ + heat → Na₂CO₃ + CO₂ (recycled)
Soda ash is an off-white to white anhydrous powder or granular material. The quality of soda ash is usually characterized by the percent of sodium oxide (Na₂O) content.
Industrial uses The most prominent characteristic of soda ash in solution is the high buffered pH response. For example, changing the sodium carbonate dosage from 0.03% to 30% only causes the solution pH to change from 10.5 to 11.7. Because of this, in mineral processing application, soda ash is used for pH control to a maximum value of 10.5.
Safety Sodium carbonate is used in injectable, oral, and rectal pharmaceutical formulations. The pure form of sodium carbonate is mildly toxic by ingestion, moderately toxic by inhalation and SC routes, and very toxic by the IP route. It is irritating to the skin and eyes. Dust and vapors of sodium carbonate may irritate mucous membranes, causing coughing and shortness of breath. It also has experimental reproductive effects.
Sodium carbonate can migrate to food from packaging materials. When used as an excipient or antacid, sodium carbonate is generally regarded as a nontoxic and nonirritating material.
LD50 (mouse, IP): 0.12 g/kg
LD50 (mouse, SC): 2.21 g/kg
LD50 (rat, oral): 4.09 g/kg
storage Sodium carbonate converts to the monohydrate form when in contact with water and produces heat. It begins to lose carbon dioxide at temperatures above 400℃ and decomposes before boiling. Store in airtight containers.
Incompatibilities Sodium carbonate decomposes when in contact with acids in the presence of water to produce carbon dioxide and effervescence. It may react violently with aluminum, phosphorous pentoxide, sulfuric acid, fluorine, and lithium.
Regulatory Status GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (injections; ophthalmic solution; oral capsules and tablets; rectal suspensions). Included in the Canadian List of Acceptable Non-medicinal Ingredients. Included in parenteral (powder for solution for injection) and nonparenteral medicines (oral effervescent tablets, soluble tablets, granules, lozenges, chewing gums) licensed in the UK.
USP32–NF27 allows either the anhydrous or the monohydrate form.