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DICLOFENAC-D4

DICLOFENAC-D4 Structure
DICLOFENAC-D4
  • CAS No.153466-65-0
  • Chemical Name:DICLOFENAC-D4
  • CBNumber:CB1677920
  • Molecular Formula:C14H11Cl2NO2
  • Formula Weight:296.15
  • MOL File:153466-65-0.mol
DICLOFENAC-D4 Property
  • Melting point 157-159°C
  • storage temp. -20°C Freezer
  • solubility DMSO: 35 mg/ml,Ethanol: 35 mg/ml,PBS (pH 7.2): 6 mg/ml
  • form A solid
  • color White to off-white
  • Water Solubility Water: 50 mg/ml
  • CAS DataBase Reference 153466-65-0
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements
  • Precautionary statements

DICLOFENAC-D4 Chemical Properties,Usage,Production

  • Description Diclofenac-d4 is intended for use as an internal standard for the quantification of diclofenac (Item Nos. 70680 | 22983) by GC- or LC-MS. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 0.9-2.7 and 1.5-20 μM, for human COX-1 and COX-2, respectively). It is also an active metabolite of diclofenac methyl ester and diclofenac amide . Diclofenac inhibits release of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) induced by A23187 in isolated rat peritoneal neutrophils and macrophages (IC50s = 60 and 10 μM, respectively). Transdermal administration of diclofenac inhibits carrageenan-induced paw edema in rats. Formulations containing diclofenac have been used in the treatment of pain associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
  • Chemical Properties Off-White Crystalline Solid
  • Uses Labeled Diclofenac, a nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor. 92% overall isotopic purity. A representative lot was 75% d4, 23% d3 and 2 % d2
  • Uses Labelled Diclofenac, a nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor.
  • Uses Labelled Diclofenac is a known nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor.
DICLOFENAC-D4 Preparation Products And Raw materials
Raw materials
Preparation Products
DICLOFENAC-D4 Suppliers
Global(59)Suppliers
  • Supplier：
    Aladdin Scientific
  • Tel：
  • Email：tp@aladdinsci.com
  • Country：United States
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    TargetMol Chemicals Inc.
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  • Email：zijue.cai@tsbiochem.com
  • Country：United States
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  • Supplier： J & K SCIENTIFIC LTD.
  • Tel： 18210857532
  • Email：jkinfo@jkchemical.com
  • Country：China
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  • Supplier： ChemStrong Scientific Co.,Ltd
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  • Email：sales@chem-strong.com
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  • Supplier： Artis Biotech Co. Ltd.
  • Tel：19138486554<br/>18108108965
  • Email：sales@artisbio.com
  • Country：China
  • ProdList：5329
  • Advantage：58
DICLOFENAC-D4 Spectrum
153466-65-0, DICLOFENAC-D4Related Search:
  • Pharmaceuticals
  • Metabolites & Impurities
  • Intermediates & Fine Chemicals
  • 杂质对照品
  • 抑制剂
  • 药靶配体
  • 标准品
  • C14H7Cl2D4NO2
  • C14H7D4Cl2NO2
  • 双氯芬酸-[D4]/精确称量
  • 丙酮中醋氯芬酸-D4同位素
  • 二氯芬酸-D4D4-DICLOFENAC
  • [2H4]-双氯芬酸
  • 双氯芬酸D4
  • 153466-65-0
  • 2-[2,3,4,5-tetradeuterio-6-(2,6-dichloroanilino)phenyl]aceticaci
  • Diclofenac D4Q: What is Diclofenac D4 Q: What is the CAS Number of Diclofenac D4 Q: What is the storage condition of Diclofenac D4 Q: What are the applications of Diclofenac D4
  • [2H4]-Diclofenac
  • D4-Diclofenac
  • 2-[2,3,4,5-tetradeuterio-6-(2,6-dichloroanilino)phenyl]acetic acid
  • 2-((2,6-Dichlorophenyl)aminobenzeneacetic Acid-d4,
  • DICLOFENAC-D4 (PHENYL-D4)
  • DICLOFENAC-D4
  • Diclofenac-D4 (Major)

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