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insulin glargine

insulin glargine Structure
insulin glargine
  • CAS No.160337-95-1
  • Chemical Name:insulin glargine
  • CBNumber:CB1547528
  • Molecular Formula:C267H404N72O78S6
  • Formula Weight:6062.89026
  • MOL File:160337-95-1.mol
insulin glargine Property
Safety
  • HS Code  :2937120000
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H373
  • Precautionary statements P260-P314-P501

insulin glargine Chemical Properties,Usage,Production

  • Uses long-acting basal insulin analogue, helping control the blood sugar level of those with type 1 and type 2 diabetes mellitus. It is an analogue of human insulin made by replacing the asparagine residue at position A21 of the A-chain with glycine and adding
  • Uses Insulin Glargine (>90%) is an insulin analogue used in the treatment of adults with type 1 or type 2 diabetes.
  • brand name Lantus (Hoechst Marion Roussel).
  • Biological Activity Insulin glargine is an approved long-acting insulin analog used for management of Diabetes Type 1 and Type 2. Insulin glargine is a human insulin analog where A-chain asparagine 21 was replaced by glycine and B-chain carboxy terminal was extended by two arginine residues.
  • in vivo

    Insulin glargine (2-12.5 IU/kg; subcutaneous injection; 3-12 months) does not present a carcinogenic risk in rodents[2].
    Insulin glargine (450 mg/kg; subcutaneous injection; 6 months) has an improving effect in a mouse model of diabetes[3].

    Animal Model:Seven-week-old male db/db mice[3]
    Dosage:450 mg/kg
    Administration:Subcutaneous injection (s.c.); 6 months
    Result:Significantly improved glucose tolerance.
    Upregulated pancreatic β-cell functional genes, such as INS1, Pdx1, Pax4 and Pax6.
insulin glargine Preparation Products And Raw materials
Raw materials
Preparation Products
insulin glargine Suppliers
Global(75)Suppliers
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  • Supplier：
    Watson Biotechnology Co.,Ltd
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  • Email：sales01@watsonbiotech.cn
  • Country：China
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insulin glargine Spectrum
160337-95-1, insulin glargineRelated Search:
  • 标准品
  • C267H404N72O78S6
  • AE标记的甘精胰岛素单克隆抗体
  • 甘精胰岛素单克隆抗体
  • BIOTIN标记的甘精胰岛素单克隆抗体
  • HRP标记的甘精胰岛素单克隆抗体
  • AP标记的甘精胰岛素单克隆抗体
  • 甘精胰岛素 EP标准品
  • 甘精胰岛素(干冰运输)
  • 甘精胰岛素峰鉴别 EP标准品
  • 甘精胰岛素
  • 来得时(甘精胰岛素)
  • 160337-95-1
  • Research Grade Insulin Glargine
  • Insulin glargine/C1A
  • Insulin Glargine (15.27 mg) (COLD SHIPMENT REQUIRED)
  • Solostar
  • Lantus
  • Insulin, glycyl(A21)-arginyl(B31,B32)-
  • Insulin glargine for peak identification (Y0001544)
  • Insulin (human),21A-glycine-30Ba-Larginine- 30Bb-L-arginine-
  • insulin glargine USP/EP/BP
  • Insulin glargine United States Pharmacopeia (USP) Reference Standard
  • Insulin glargine for peak identification CRS
  • Insulin Glargine RS
  • Insulin glargine CRS
  • Insulin Glargine, recombinant
  • Unii-2zm8cx04rz
  • Solostar [insulin delivery pen]
  • A21-Gly-B31-Arg-B32-Arg-insulin
  • Insulin Glargine EP/USP
  • insulin glargine

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