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DROFENINE HYDROCHLORIDE

DROFENINE HYDROCHLORIDE Property

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Hazard and Precautionary Statements (GHS)

DROFENINE HYDROCHLORIDE Chemical Properties,Usage,Production

Originator Trasentine A,Ciba
Uses Drofenine is a widely used anticholinergic drug. It acts on smooth muscle to stop muscle spasms.
Uses Spasmolytic
Manufacturing Process 17.4 parts of diphenylacetic acid 2-(diethylamino)ethyl ester were solved in 200 parts of acetic acid and hydrogenated over platinum catalyst. After the calculated volume of hydrogen was passed, the catalyst was filtered off and the solvent was removed to dryness. Ether, water and a potassium carbonate solution were added to the remaining oil and were thoroughly shaken. The ether layer was washed with water and dried over potassium carbonate. The solvent was removed, the remaining oil was distilled in vacuum to give 2- (diethylamino)ethyl α-phenylcyclohexaneacetate; BP 150°-160°C/0.2 mm Hg.
In practice it is usually used as hydrochloride.
Therapeutic Function Spasmolytic
IC 50 BChE

DROFENINE HYDROCHLORIDE Preparation Products And Raw materials

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DROFENINE HYDROCHLORIDE Spectrum

548-66-3, DROFENINE HYDROCHLORIDERelated Search:

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C20H31NO2HCl
盐酸六氢芬宁,10 MM DMSO 溶液
2-(二乙基氨基)乙基2-环己基-2-苯基乙酸盐酸盐
盐酸六氢芬宁标准品
六氢解痉素
六氢芬宁盐酸盐
盐酸六氢芬宁杂质
盐酸六氢芬宁
548-66-3
Drofenine hydrochloride, 10 mM in DMSO
2-(Diethylamino)ethyl 2-cyclohexyl-2-phenylacetate hydrochloride
Drofenine,Cholinesterase (ChE),Drofenine hydrochloride,Inhibitor,inhibit,Hexahydroadiphenine
Drofeninhydrochlorid
DrofeninHCl
2-diethylaminoethyl alpha-cyclohexylphenylacetate hydrochloride
2-(2-cyclohexyl-2-phenylacetoxy)ethyldiethylammonium chloride
trasentinh
trasentine-6hhydrochloride
it-19
cyclovegantine
cyclospasmol(tempelhof)
cyclohexylphenylacetyldiethylaminoethanolhydrochloride
cycloadipheninehydrochloride
cycloadiphenine
alpha-phenyl-cyclohexylessigsaeure-2-diaethylamino-aethylester-hydrochlorid
alpha-phenylcyclohexaneaceticacid2-(diethylamino)ethylesterhydrochloride
alpha-cyclohexylbenzeneaceticacid2-(diethylamino)ethylesterhydrochloride
adipheninehhydrochloride
2-diethylaminoethyl(alpha-phenylcyclohexane)acetatehydrochloride
2-(diethylamino)ethylalpha-cyclohexylbenzeneacetate
DROFENINE HCL
hexahydroadiphenine
DROFENINE HYDROCHLORIDE
HEXAHYDROADIPHENINE HYDROCHLORIDE
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