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2-Amino-2-phenylacetic acid

2-Amino-2-phenylacetic acid Structure
2-Amino-2-phenylacetic acid
  • CAS No.2835-06-5
  • Chemical Name:2-Amino-2-phenylacetic acid
  • CBNumber:CB1420201
  • Molecular Formula:C8H9NO2
  • Formula Weight:151.17
  • MOL File:2835-06-5.mol
2-Amino-2-phenylacetic acid Property
  • Melting point 290 °C (subl.)(lit.)
  • alpha [α]D20-0.5～+0.5゜ (c=5, dil. HCl)
  • Boiling point 273.17°C (rough estimate)
  • Density 1.2023 (rough estimate)
  • refractive index 1.5810 (estimate)
  • storage temp. Keep in dark place,Inert atmosphere,Room temperature
  • solubility almost transparency in Sodium hydroxide solution
  • pka 1.94±0.10(Predicted)
  • form Crystalline Powder
  • color White to off-white
  • Water Solubility 115g/L(100 ºC)
  • Merck 14,7291
  • BRN 3197862
  • InChIKey ZGUNAGUHMKGQNY-UHFFFAOYSA-N
  • CAS DataBase Reference 2835-06-5(CAS DataBase Reference)
  • FDA UNII 96S7ZZ1KHE
  • NIST Chemistry Reference Benzeneacetic acid, «alpha»-amino-, (.+/-.)-(2835-06-5)
  • EPA Substance Registry System 2-Phenylglycine (2835-06-5)
  • UNSPSC Code 12352209
  • NACRES NA.22
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P305+P351+P338
2-Amino-2-phenylacetic acid Price More Price(6)
  • Brand: Sigma-Aldrich(India)
  • Product number: P25507
  • Product name : 2-Phenylglycine
  • Purity: 95%
  • Packaging: 100G
  • Price: ₹4622.28
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: P0326
  • Product name : DL-2-Phenylglycine
  • Purity: 
  • Packaging: 25G
  • Price: ₹1600
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: P0326
  • Product name : DL-2-Phenylglycine
  • Purity: 
  • Packaging: 500G
  • Price: ₹10200
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: ottokemi
  • Product number:  P 1668
  • Product name : DL-Phenyl glycine
  • Purity: , GR 99%+
  • Packaging: 25gm
  • Price: ₹1908
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: ottokemi
  • Product number:  P 1668
  • Product name : DL-Phenyl glycine
  • Purity: , GR 99%+
  • Packaging: 100gm
  • Price: ₹4302
  • Updated: 2022/05/26
  • Buy: Buy

2-Amino-2-phenylacetic acid Chemical Properties,Usage,Production

  • Description 2-Amino-2-phenylacetic acid is a natural compound that has been identified as a selective inhibitor of cyclooxygenase 2 (COX-2), and it exhibits antiinflammatory activity. It has been shown to inhibit COX-2 at low concentrations and to be less potent than aspirin in inhibiting COX-1. It is also an amide, with a molecular weight of 296. In order to determine the structure of it, XRD data was collected from the monosodium salt form of the compound. The ester hydrochloride form was used for enzyme activity assays because it is more soluble in water than the free base form. The synthesis of 2-Amino-2-phenylacetic acid was achieved through a two step process involving amide formation and hydrolysis.
  • Chemical Properties white amorphous powder
  • Uses DL-α-Phenylglycine is used as a reagent in the synthesis of benzoquinone-amino acid conjugates which have antibacterial activity.
  • Definition ChEBI: An amino acid with a structure in which a phenyl ring is bonded to the alpha-carbon of glycine.
  • Synthesis Reference(s) Organic Syntheses, Coll. Vol. 3, p. 84, 1955
    Synthetic Communications, 2, p. 423, 1972 DOI: 10.1080/00397917208081791
  • reaction suitability reaction type: solution phase peptide synthesis
2-Amino-2-phenylacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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2-Amino-2-phenylacetic acid Spectrum
2835-06-5, 2-Amino-2-phenylacetic acidRelated Search:
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