Chemical Properties
Light grey crystalline powder
Uses
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
Preparation of Example 110 Ethyl L-tryptophan hydrochloride: L-tryptophan (14.3 g, 0.07 mol) was dissolved in 200 ml of ethanol containing about 7 g of anhydrous hydrogen chloride and the reaction was carried out at reflux for 5 hours. After completion of the reaction, the mixture was cooled and the precipitated solid was purified by recrystallization from a solvent mixture of ethanol/ether. The product was obtained as 17.4 g in 92.5% yield, melting point not provided. The product was chemically named L-2-amino-3-indolepropionic acid ethyl ester hydrochloride.
References
[1] Patent: US4824850, 1989, A
