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D-Galactose

CAS No.59-23-4
Chemical Name:D-Galactose
CBNumber:CB1327034
Molecular Formula:C6H12O6
Formula Weight:180.16
MOL File:59-23-4.mol

D-Galactose Property

Melting point 168-170 °C(lit.)
alpha +79.0～+81.0°(D/20℃) (c=10, dil. NH4OH)
Boiling point 232.96°C (rough estimate)
Density 1,5 g/cm³
refractive index 80 ° (C=10, H2O)
storage temp. room temp
solubility H₂O: 100 mg/mL
form powder
pka pK1:12.35 (25°C)
color White
PH 4.5-6.0 (H2O)Aqueous solution
Odor Odorless
PH Range 5 - 7 at 180 g/l at 25 °C
optical activity [α]20/D +80±1°, 24 hr, c = 5% in H2O
biological source bovine (Ruminant- CowOxBuffalo)
Water Solubility Soluble in water.
Merck 14,4335
BRN 1724619
InChIKey GZCGUPFRVQAUEE-DPYQTVNSSA-N
LogP -2.490 (est)
CAS DataBase Reference 59-23-4(CAS DataBase Reference)
FDA UNII X2RN3Q8DNE
NIST Chemistry Reference D-Galactose(59-23-4)
EPA Substance Registry System D-Galactose (59-23-4)
UNSPSC Code 12352201
NACRES NA.79

Safety

Hazard Codes :Xi
Risk Statements :36/37/38
Safety Statements :22-24/25-36/37/39-27-26
WGK Germany :3
RTECS :LW5490000
F :3
TSCA :Yes
HS Code :29400090

NFPA 704:

	0
1		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H302-H312-H332
Precautionary statements P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501

D-Galactose Price More Price(33)

Brand: Sigma-Aldrich(India)
Product number: G6404
Product name : D-(+)-Galactose
Purity: BioXtra, pH 5.0-7.0 (20?°C, 1?M in H2O), ≥99%
Packaging: 10G
Price: ₹5693.95
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: PHR1206
Product name : Galactose
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 500MG
Price: ₹8508.45
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: G6404
Product name : D-(+)-Galactose
Purity: BioXtra, pH 5.0-7.0 (20?°C, 1?M in H2O), ≥99%
Packaging: 25G
Price: ₹8562.58
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: G0750
Product name : D-(+)-Galactose
Purity: ≥99%
Packaging: 10MG
Price: ₹1818.6
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: G6404
Product name : D-(+)-Galactose
Purity: BioXtra, pH 5.0-7.0 (20?°C, 1?M in H2O), ≥99%
Packaging: 100G
Price: ₹23100.55
Updated: 2022/06/14
Buy: Buy

D-Galactose Chemical Properties,Usage,Production

Description D-Galactose is a monosaccharide sugar that serves as an energy source and glycosylation component. It is a C-4 epimer of glucose and often used as a source of carbon in culture media. Galactose is a component of the disaccharide lactose and released upon hydrolysis by β-galactosidase enzymes. It is converted to glucose via the Leloir pathway or metabolized via an alternative pathway, such as the DeLey-Doudoroff pathway.
Description D-Galactose is a natural aldohexose and C-4 epimer of glucose. D-galactose is converted enzymatically into D-glucose for metabolism or polysaccharides for storage. Chronic, systemic exposure to D-galactose accelerates senescence in invertebrates and mammals and has been used as a model for aging. In bacteria, D-galactose is imported by a methyl-galactoside transport system to drive chemotaxis.
Chemical Properties White powder
Uses Galactose is a simple monosaccharide used as a component of the galactosyltransferase labeling buffer. It serves as an energy source and an important constituent of glycolipids and glycoproteins. Since it is a component of antigens, it plays a vital role in the determination of blood type within the ABO blood group system.
Uses A C-4 epimer of Glucose (G595000) found in milk and sugar beets as well as being synthesized by the body. Potential use in oral therapy for nephrotic syndrome in focal and segmental glomerulosclerosis.
Uses D-Galactose is suitable for use in cell culture systems requiring sugar additives.
Definition A monosaccharide commonly occurring in milk sugar or lactose.
Application Galactose has been used:
as a component of galactosyltransferase labeling buffer.
as a supplement in MRS broth for the growth of thermophilic lactobacilli.
to induce the expression of uncoupling protein (UCP) in yeast transformants.
General Description Galactose is a constituent of lactose. It is one of the main nutrients for newborn infants and young children. It is produced in the body for the formation of lactose and is also a component of glycolipids (cerebrosides) and glycoproteins.
Biological Activity Galactose is a simple monosaccharide that serves as an energy source and as an essential component of glycolipids and glycoproteins. Galactose contributes to energy metabolism via its conversion to glucose by the enzymes that constitute the Leloir pathway. Defects in the genes encoding these proteins lead to the metabolic disorder galactosemia.
Biochem/physiol Actions Galactose is a simple monosaccharide that serves as an energy source and as an essential component of glycolipids and glycoproteins. Galactose contributes to energy metabolism via its conversion to glucose by the enzymes that constitute the Leloir pathway. Defects in the genes encoding these proteins lead to the metabolic disorder galactosemia.
Purification Methods D-Galactose is crystallised twice from aqueous 80% EtOH at -10o, then dried in a vacuum oven at 90o over P2O5 for 10hours. [Link Biochemical Preparations 3 75 1953, Hansen et al. Biochemical Preparations 4 2 1955.] Also purify it by recrystallising the dried solid (150g) in hot H2O (150mL), then adding hot MeOH (250mL) and hot EtOH (500mL), stirring to mix, filtering through a bed of charcoal, and the clear filtrate is stirred to initiate crystallisation. After standing overnight at 10o, the crystals of the -anomer are filtered off by suction, washed with MeOH, then EtOH, and dried (yield 130g), and more can be obtained by evaporation of the filtrate and washing as before. [Wolfrom & Thompson Methods in Carbohydrate Chemistry I 120 1962, Academic Press, Beilstein 1 IV 4336.]