ChemicalBook > CAS DataBase List > 2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide

2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide

2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide Structure
2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide
  • CAS No.1462267-08-8
  • Chemical Name:2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide
  • CBNumber:CB13049643
  • Molecular Formula:C24H22BrN3O4
  • Formula Weight:496.35
  • MOL File:1462267-08-8.mol
2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide Property
  • Boiling point 724.2±60.0 °C(Predicted)
  • Density 1.445±0.06 g/cm3(Predicted)
  • pka 12.31±0.70(Predicted)
  • form Solid
  • color White to off-white
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide Chemical Properties,Usage,Production

  • Uses ML266 is glucocerebrosidase (GCase) molecule chaperone with IC50 of 2.5 μM. ML266 binds to GCase and transports of the mutant protein to the lysosome, and resume the activity of GCase. ML266 dose not inhibit the GCase enzyme’s action. ML266 has the potential for the research of gaucher disease[1].
  • References [1] Rogers S, et al. Discovery, SAR, and Biological Evaluation of Non-inhibitory Chaperones of Glucocerebrosidase. 2012 Mar 27 [updated 2013 Mar 7]. PMID:23762943
2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide Preparation Products And Raw materials
Raw materials
Preparation Products
2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide Suppliers
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2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide Spectrum
1462267-08-8, 2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamideRelated Search:
  • 化学试剂
  • 抑制剂
  • 药靶配体
  • 化合物ML266,10 MM DMSO 溶液
  • 2-(2-((4-溴苯基)氨基)-2-氧代乙氧基)-N-(2-(甲基(苯基)氨基]-2-氧代乙基)苯甲酰胺
  • 化合物ML266
  • 2-(2-(4-溴苯基氨基)-2-氧乙氧基)-N-(2-(甲基(苯基)氨基)-2-氧乙基)苯甲酰胺
  • 1462267-08-8
  • ML266, 10 mM in DMSO
  • 2-[(2-{[(4-bromophenyl)carbamoyl]methoxy}phenyl)formamido]-N-methyl-N-phenylacetamide
  • CID-4694321
  • Benzamide, 2-[2-[(4-bromophenyl)amino]-2-oxoethoxy]-N-[2-(methylphenylamino)-2-oxoethyl]-
  • CS-2740
  • 133974
  • ML266
  • CID-46943215
  • 2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide

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