ChemicalBook > CAS DataBase List > (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Structure
(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
  • CAS No.327623-37-0
  • Chemical Name:(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
  • CBNumber:CB12657010
  • Molecular Formula:C20H18F7NO2
  • Formula Weight:437.35
  • MOL File:327623-37-0.mol
(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Property
  • Boiling point 387.9±42.0 °C(Predicted)
  • Density 1.37±0.1 g/cm3(Predicted)
  • pka 6.93±0.60(Predicted)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Chemical Properties,Usage,Production

  • Uses Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1''S)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.
(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Preparation Products And Raw materials
Raw materials
Preparation Products
(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Suppliers
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(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Spectrum
327623-37-0, (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)MorpholineRelated Search:
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  • 阿瑞吡坦杂质10对甲苯磺酸盐
  • 福沙普坦杂质30
  • 阿瑞吡坦杂质9
  • 杂质杂质
  • 过量杂质E
  • 阿瑞匹坦杂质1盐酸盐
  • APREPITANT M2代谢产物(1S,2S,3R)-异构体
  • 福沙匹坦杂质30
  • 阿瑞杂质11
  • (2S,3R)-2-[(1S)-1-[3,5-双(三氟甲基)苯基]乙氧基]-3-(4-氟苯基)吗啉盐酸盐
  • (2S,3R)-2-[(1S)-1-[3,5-双(三氟甲基)苯基]乙氧基]-3-(4-氟苯基)吗啉
  • 327623-37-0
  • Aprepitant Impurity 10 Hydrochloride
  • Des-1,2,4-triazol-3-one-5-methyl(2S,3R,1&rsquo
  • Morpholine, 2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, (2S,3R)-
  • Aprepitant M2 Metabolite Enantiomer
  • Aprepitant Impurity 1 Hydrochloride
  • Fosaprepitant Impurity 30
  • Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer
  • Aprepitant Impurity 11
  • Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'S)-Aprepitant
  • Aprepitant Impurity 1
  • (2S,3R)-2-[(1S)-1-(3,5-bis-trifluoro-Methylphenyl)ethoxy]-3-(4-fluorophenyl)Morpholine
  • (2S,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride
  • (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine

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