2-Amino-2-methylsuccinic acid

Product Name2-Amino-2-methylsuccinic acid
CAS2792-66-7
CBNumberCB1258071
MFC5H9NO4
MW147.13
MDL NumberMFCD00056709
MOL File2792-66-7.mol

Chemical Properties

Melting point:	234-237 °C (decomp)
Boiling point:	259.2±30.0 °C(Predicted)
Density	1.414±0.06 g/cm3(Predicted)
pka	2.32±0.28(Predicted)
form	Solid
color	White to off-white
CAS DataBase Reference	2792-66-7

Safety

WGK Germany	3
HS Code	2922499990

2-Amino-2-methylsuccinic acid Price

Product number	Packaging	Price	Product description	Buy
Sigma-Aldrich(India) M6001	100MG	₹4405.78	α-Methyl-DL-aspartic acid	Buy
Sigma-Aldrich(India) M6001	1G	₹24258.83	α-Methyl-DL-aspartic acid	Buy

More Price(2)

2-Amino-2-methylsuccinic acid Chemical Properties,Usage,Production

Uses

α-Methyl-DL-aspartic acid is a specific inhibitor of argininosuccinate synthase (ASS), and also is the rate-limiting enzyme for the recycling of 1-citrulline to 1-arginine[1].

in vivo

α-methyl-dl-aspartic acid (147 mg/kg, i.v.) can diminish the l-citrulline-induced retinal vasodilation in Wistar rats^[1].

Animal Model:	Wistar rats
Dosage:	147 mg/kg
Administration:	147 mg/kg, i.v.
Result:	Attenuated the increase of retinal arteriolar diameter induced by L-citrulline.

References

[1] Asami Mori, et al. l-Citrulline dilates rat retinal arterioles via nitric oxide- and prostaglandin-dependent pathways in vivo. J Pharmacol Sci. 2015 Apr;127(4):419-23. DOI:10.1016/j.jphs.2015.02.012
[2] Juliano R Guerreiro, et al. Argininosuccinate synthetase is a functional target for a snake venom anti-hypertensive peptide: role in arginine and nitric oxide production. J Biol Chem. 2009 Jul 24;284(30):20022-33. DOI:10.1074/jbc.M109.021089

2-Amino-2-methylsuccinic acid Suppliers

Global(66)Suppliers

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China 55 Germany 1 Switzerland 1 United Kingdom 2 United States 7

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Supplier	Tel	Email	ProdList	Advantage
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	49898	58
Aladdin Scientific		tp@aladdinsci.com	50068	58
DONBOO AMINO ACID COMPANY	13063595538	donboo@donboo.com	9358	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	51389	80
Kanghua (Shanghai) New Drug Development Co., Ltd.	021-61263370 18516560301	xingli@glbiochem.com	5637	58
Shanghai Guchen Biotechnology Co., LTD	021-34675735 19147740836	1986399151@qq.com	9839	58
Shanghai Inchman Chemical Technology Co., LTD	18299177127	info@richmanchem.com	3000	58
Hubei Tuobang Chemical Co., Ltd.	027-59106185 13986192185	1158480077@qq.com	9542	58
Hubei Xinkang Pharmaceutical Chemical Co., Ltd	027-59308705 18871579363	1248680011@qq.com	9247	58
Hubei DAHAO Chemical Co., Ltd.	027-59106191 13986034860	1400828855@qq.com	8660	58

2-Amino-2-methylsuccinic acid Spectrum

2-AMINO-2-METHYLSUCCINIC ACID(2792-66-7)MS 2-AMINO-2-METHYLSUCCINIC ACID(2792-66-7)¹HNMR 2-AMINO-2-METHYLSUCCINIC ACID(2792-66-7)IR1 2-AMINO-2-METHYLSUCCINIC ACID(2792-66-7)IR2

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