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RO 0437626

RO 0437626 Structure
RO 0437626
  • CAS No.134362-79-1
  • Chemical Name:RO 0437626
  • CBNumber:CB12458150
  • Molecular Formula:C27H35N5O4S
  • Formula Weight:525.66
  • MOL File:134362-79-1.mol
RO 0437626 Property
  • storage temp. Store at -20°C
  • solubility Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • form Powder
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

RO 0437626 Chemical Properties,Usage,Production

  • Uses Ro 0437626 is a P2X1 purinergic receptor antagonist.
  • Biological Activity Selective P2X 1 purinergic receptor antagonist (IC 50 = 3 μ M) that displays > 30-fold selectivity over P2X 2 , P2X 3 and P2X 2/3 receptors (IC 50 > 100 μ M).
  • in vivo

    Ro 0437626 (1 and 10 μmol/kg; i.v.) causes a reduction in postinfusion isovolumetric contractions[3].

    Animal Model:Female rat (urethane-anaesthetized)[3]
    Dosage:1 and 10 μmol/kg
    Administration:I.v.
    Result:Caused a reduction in postinfusion isovolumetric contractions.
RO 0437626 Preparation Products And Raw materials
Raw materials
Preparation Products
RO 0437626 Suppliers
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RO 0437626 Spectrum
134362-79-1, RO 0437626Related Search:
  • 抑制剂
  • C27H35N5O4S
  • 化合物 RO 0437626
  • 化合物 T23241
  • 134362-79-1
  • 1H-Benzimidazole-2-carboxamide, N-[(1R)-2-[[(1S,2R,3S)-1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]amino]-2-oxo-1-(4-thiazolylmethyl)ethyl]-
  • N-[(1R)-2-[[(1S,2R,3S)-1-(Cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]amino]-2-oxo-1-(4-thiazolylmethyl)ethyl]-1H-benzimidazole-2-carboxamide
  • RO 0437626

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