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PAROXETINE-D4 HCL

PAROXETINE-D4 HCL Structure
PAROXETINE-D4 HCL
  • CAS No.110429-35-1
  • Chemical Name:PAROXETINE-D4 HCL
  • CBNumber:CB1178023
  • Molecular Formula:C19H23ClFNO4
  • Formula Weight:383.84
  • MOL File:110429-35-1.mol
PAROXETINE-D4 HCL Property
  • Melting point 121-131 C
  • storage temp. under inert gas (nitrogen or Argon) at 2-8°C
  • solubility Slightly soluble in water, freely soluble in methanol, sparingly soluble in ethanol (96 per cent) and in methylene chloride.
  • form powder
  • color white
  • λmax 292nm(H2O)(lit.)
  • Merck 14,7043
  • CAS DataBase Reference 110429-35-1
  • FDA UNII X2ELS050D8
  • UNSPSC Code 41116107
  • NACRES NA.77
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H317-H319-H411
  • Precautionary statements P261-P273-P280-P301+P312-P302+P352-P305+P351+P338
PAROXETINE-D4 HCL Price More Price(6)
  • Brand: Sigma-Aldrich(India)
  • Product number: P9623
  • Product name : Paroxetine hydrochloride hemihydrate
  • Purity: ≥98% (HPLC), powder
  • Packaging: 10MG
  • Price: ₹15349.85
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: PHR1804
  • Product name : Paroxetine hydrochloride
  • Purity: Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging: 500MG
  • Price: ₹20892.25
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: P9623
  • Product name : Paroxetine hydrochloride hemihydrate
  • Purity: ≥98% (HPLC), powder
  • Packaging: 50MG
  • Price: ₹59775.65
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 5.06125
  • Product name : Paroxetine Hydrochloride - CAS 110429-35-1 - Calbiochem
  • Purity: Paroxetine Hydrochloride is a very potent uptake inhibitor highly selective for 5-HT transporter.
  • Packaging: 10MG
  • Price: ₹12440
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: P1977
  • Product name : Paroxetine Hydrochloride Hemihydrate
  • Purity: 
  • Packaging: 1G
  • Price: ₹10300
  • Updated: 2022/05/26
  • Buy: Buy

PAROXETINE-D4 HCL Chemical Properties,Usage,Production

  • Chemical Properties White or almost white, crystalline powder.
  • Uses Antidepressant;5-HT uptake inhibitor
  • Uses Paroxetine hydrochloride hemihydrate has been used: as an antidepressant to study its effects on neural stem cells (NSCs) from embryonic rat hippocampus in vitro; as a CYP 2D6 inhibitor to study its effects on the in vitro?production by human recombinant CYP 2D6 of the phenolic metabolites; as an antidepressant to study its effects on the expression of pituitary adenylate cyclase activating polypeptide (PACAP), its receptors and brain-derived neurotrophic factor (BDNF) in rat primary hippocampal neurons
  • Uses Paroxetine Hydrochloride, is a selective serotonin reuptake inhibitor (SSRI) antidepressant used to treat depression, panic attacks, obsessive-compulsive disorder (OCD), anxiety disorders, post-traumatic stress disorder, and a severe form of premenstrual syndrome (premenstrual dysphoric disorder).
  • General Description Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
  • Biochem/physiol Actions Paroxetine hydrochloride hemihydrate is one of the most potent and selective of the selective serotonin reuptake inhibitors (SSRI); antidepressant
  • in vivo

    Paroxetine treatment obviously attenuates the symptoms of CIA rats. Paroxetine treatment clearly prevents the histological damage of joints and alleviates T cells infiltration into synovial tissue. Paroxetine reveals a strong effect on inhibiting CX3CL1 production in synovial tissues[1]. Paroxetine (20 mg/kg/day) reduces the myocyte cross-sectional area in rat and ROS formation in the remote myocardium. Paroxetine reduces the susceptibility to ventricular tachycardia. Paroxetine treatment following MI decreases LV remodeling and susceptibility to arrhythmias, probably by reducing ROS formation[2]. In CCI paroxetine-treated group, paroxetine (10 mg/kg, i.p.) produces hyperalgesia at days 7 and 10 (P<0.01), but a decrease in pain behavior is seen at day 14. Moreover, paroxetine (10 mg/kg) significantly attenuates tactile hypersensitivity when compared to CCI vehicle-treated group[5].

PAROXETINE-D4 HCL Preparation Products And Raw materials
Raw materials
Preparation Products
PAROXETINE-D4 HCL Suppliers
Global(320)Suppliers
  • Supplier：
    Henan Tianfu Chemical Co.,Ltd.
  • Tel：+86-0371-55170693<br/>+86-19937530512
  • Email：info@tianfuchem.com
  • Country：China
  • ProdList：21628
  • Advantage：55
  • Supplier：
    career henan chemical co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：factory@coreychem.com
  • Country：China
  • ProdList：29808
  • Advantage：58
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
  • Country：United States
  • ProdList：32159
  • Advantage：58
PAROXETINE-D4 HCL Spectrum
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  • Paroxetine HCl hemihydrate - Bio-X ?
  • PAROXETINE HYDROCHLORIDE (HEMIHYDRATE) USP
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  • Paroxetine hydrochloride hemihydrate, 10 mM in DMSO
  • Paroxetine hydrochloride, 5-HT uptake inhibitor
  • Paroxetine hydrochloride (DMSO Solution)
  • (-)-(3S,4R)-Paroxetine hydrochloride hemihydrate in methanol
  • Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride, hydrate (2:1), (3S-trans)-
  • Paroxetine-D4 hydrochloride
  • PAROXETINE HCL HEMIHYDRATE
  • PAROXETINE HYDROCHLORIDE HEMIHYDRATE
  • paroxetine hydrochloride hydrate
  • Paroxetine Hydrochloride (1500218)
  • Paroxetine for system suitability (Y0000630)
  • (3S,4R)-3-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine hydrochloride hemihydrate
  • aroxetine hydrochloride hemihydrate
  • PAROXETINE-D4 HCL USP/EP/BP
  • Paroxetine hydrochloride salt hemihydrate
  • (-)-(3S,4R)-Paroxetine hydrochloride hemihydrate

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