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salaspermic acid
salaspermic acid
- CAS No.71247-78-4
- Chemical Name:salaspermic acid
- CBNumber:CB11363543
- Molecular Formula:C30H48O4
- Formula Weight:472.7
- MOL File:71247-78-4.mol
salaspermic acid Property
- Melting point 335℃
- Boiling point 571.8±25.0 °C(Predicted)
- Density 1.15±0.1 g/cm3(Predicted)
- pka 4.79±0.70(Predicted)
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
salaspermic acid Chemical Properties,Usage,Production
- Uses Salaspermic acid is a new triterpene acid isolated from Salacia macrosperma Wight. Salaspermic acid is an inhibitor of HIV reverse transcriptase and HIV replication in H9 lymphocyte cells[1][2].
- Definition ChEBI: A hexacyclic triterpenoid that is D:A-friedooleanan-29-oic acid substituted by a hydroxy group at position 3 and an epoxy group across positions 3 and 24 (the (3beta,20alpha stereoisomer). Isolated from Salacia macr sperma and Tripterygium wilfordii, it exhibits anti-HIV activity.
- References [1] Chen K, et al. Anti-aids agents, 6. Salaspermic acid, an anti-HIV principle from Tripterygium wilfordii, and the structure-activity correlation with its related compounds. J Nat Prod. 1992;55(3):340-346. DOI:10.1021/np50081a010
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