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voacristine

voacristine Structure
voacristine
  • CAS No.545-84-6
  • Chemical Name:voacristine
  • CBNumber:CB11346836
  • Molecular Formula:C22H28N2O4
  • Formula Weight:384.47
  • MOL File:545-84-6.mol
voacristine Property
  • Melting point 112-114 °C
  • Boiling point 542.9±50.0 °C(Predicted)
  • Density 1.32±0.1 g/cm3(Predicted)
  • storage temp. Store at -20°C
  • solubility DMF: 16 mg/ml; DMSO: 16 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.33 mg/ml
  • form A crystalline solid
  • pka 14.94±0.20(Predicted)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

voacristine Chemical Properties,Usage,Production

  • Uses (?)-Voacangarine is an indole alkaloid, which exhibits cytotoxic effects against cancer cells HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 with IC50 of 5~20 mg/mL. (?)-Voacangarine inhibits the cultivation of Saccharomyces cerevisiae wildtype and repair-deficient mutants[1][2].
  • References [1] Melo AA, et al., Cytostatic, cytotoxic and mutagenic effects of voacristine, an indole alkaloid in wild-type and repair-deficient yeasts. Mutat Res. 1986 Jul;171(1):17-24. DOI:10.1016/0165-1218(86)90004-2
voacristine Preparation Products And Raw materials
Raw materials
Preparation Products
voacristine Suppliers
Global(7)Suppliers
  • Supplier： Cayman Chemical Company
  • Tel：800-364-9897
  • Email：sales@caymanchem.com
  • Country：China
  • ProdList：21645
  • Advantage：58
voacristine Spectrum
545-84-6, voacristineRelated Search:
  • 抑制剂
  • (-)-VOACANGARINE
  • 545-84-6
  • (-)-Voacangarine
  • (?)-Voacangarine
  • Ibogamine-18-carboxylic acid, 20-hydroxy-12-methoxy-, methyl ester, (20S)-
  • ()-Voacangarine
  • (20S)-20-Hydroxy-12-methoxyibogamine-18-carboxylic acid methyl ester
  • COACRISTINE
  • voacristine

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