Isopenbutolol

(+)-penbutolol on the [Ca ²⁺ ] _i -increase induced by LPC is concentration-dependent.
(+) -penbutolol inhibits the rounding of cells dose dependently (8±4%, 56±4% and 66±2% at the concentrations of 10 ^-6 M, 5×10 ^{-6 M and 10 -5 M, respectively).}

IC50: 0.74 μM (β-adrenoceptor).