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5-O-Desmethyl Donepezil

5-O-Desmethyl Donepezil Structure
5-O-Desmethyl Donepezil
  • CAS No.120013-57-2
  • Chemical Name:5-O-Desmethyl Donepezil
  • CBNumber:CB11175991
  • Molecular Formula:C23H27NO3
  • Formula Weight:365.47
  • MOL File:120013-57-2.mol
5-O-Desmethyl Donepezil Property
  • Melting point 170-172°C
  • Boiling point 545.3±50.0 °C(Predicted)
  • Density 1.190±0.06 g/cm3(Predicted)
  • storage temp. -20°C Freezer
  • solubility Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated)
  • form Solid
  • pka 8.16±0.40(Predicted)
  • color White to Pale Brown
  • CAS DataBase Reference 120013-57-2
  • FDA UNII 56R452SD5N
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

5-O-Desmethyl Donepezil Chemical Properties,Usage,Production

  • Chemical Properties Off-White Solid
  • Uses A metabolite of Donepezil (D531750), an inhibitor of acetylcholinesterase.
  • Uses A metabolite of Donepezil, an inhibitor of acetylcholinesterase
  • Definition ChEBI: 5-O-desmethyldonepezil is a member of the class of piperidines that is donepezil in which the 5-methoxy group has been demethylated to the corresponding hydroxy derivative. It is metabolite of donepezil, a drug used in the treatment of dementia. It has a role as a drug metabolite. It is a member of piperidines, a cyclic ketone, an aromatic ether and a member of guaiacols.
5-O-Desmethyl Donepezil Preparation Products And Raw materials
Raw materials
Preparation Products
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5-O-Desmethyl Donepezil Spectrum
120013-57-2, 5-O-Desmethyl DonepezilRelated Search:
  • Pharmaceuticals
  • Metabolites & Impurities
  • Intermediates & Fine Chemicals
  • Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • Heterocycles
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  • 多奈哌齐杂质59
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  • 120013-57-2
  • Donepezil 5-hydroxy Impurity
  • Donepezil Impurity 59
  • 1H-Inden-1-one, 2,3-dihydro-5-hydroxy-6-methoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-
  • 2-[(1-benzylpiperidin-4-yl)methyl]-5-hydroxy-6-methoxy-2,3-dihydroinden-1-one
  • Donepezil 5-O-Desmethyl Imp
  • Donepezil Impurity 28
  • Donepezil 5-O-Desmethyl Impurity
  • 2-((1-benzylpiperidin-4-yl)methyl)-5-hydroxy-6-methoxy-2,3-dihydro-1H-inden-1-one hydrochloride
  • 2-((1-benzylpiperidin-4-yl)methyl)-5-hydroxy-6-methoxy-2,3-dihydro-1H-inden-1-one
  • 1-Benzyl-4-[(5-hydroxy-6-methoxy-1-oxo-indan-2-yl)methylpiperidine