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Premarin
Premarin
- CAS No.12126-59-9
- Chemical Name:Premarin
- CBNumber:CB0483920
- Molecular Formula:C18H19NaO5S
- Formula Weight:370.4
- MOL File:12126-59-9.mol
Premarin Property
- CAS DataBase Reference 12126-59-9(CAS DataBase Reference)
- FDA UNII IU5QR144QX
- Proposition 65 List Conjugated Estrogens
- NCI Drug Dictionary conjugated estrogens
- ATC code G03CA57
-
Symbol(GHS)
- Signal wordDanger
- Hazard statements H360-H335-H319-H315-H350
- Precautionary statements P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Premarin Chemical Properties,Usage,Production
- Description Conjugated estrogens generally occur as butter-colored powders that are soluble in water. The sodiumequilin sulfate component is unstable to light and air.Piperazine estrone sulfate occurs as a white to yellowishwhite crystalline powder that is slightly soluble in water.Piperazine estrone sulfate melts at 245℃ with decomposition. Conjugated estrogens are naturally occurring substances excreted in the urine of pregnant mares; piperazineestrone sulfate is not known to occur naturally.
- Chemical Properties Conjugated estrogens generally occur as butter-colored powders
- Chemical Properties Almost white or brownish, amorphous powder.
- Uses Conjugated Estrogen is a mixture of estrogen derivatives-mostly estrone and equilin sulfate.
- Definition ChEBI: Equilin sodium sulfate is a steroid sulfate. It is functionally related to an equilin.
- Safety Profile Suspected human carcinogen producing tumors of the vascular system and liver. Human reproductive effects: changes in female fertility. When heated to decomposition it emits toxic fumes of NazO. See also indvidual components.
- Potential Exposure Conjugated estrogens are naturally occurring substances excreted in the urine of pregnant mares; piperazine estrone sulfate is not known to occur naturally. Conjugated estrogens are used to treat symptoms of the climacteric, vulvae dystrophies; female hypogonadism; and dysfunctional uterine bleeding. They also are used for treatment following: ovariectomy, for chemotherapy of mammary cancer and prostate carcinogema; and for prevention of postpartum breast engorgement. In addition, conjugated estrogens have been found in cosmetic preparations
- First aid If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.
- storage Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. A regulated, marked area should be establishedwhere this chemical is handled, used, or stored in compliance with OSHA Standard 1910.1045.
- Shipping UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required. UN3249 Medicine, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials. PGIII.
- Incompatibilities Estrogens are Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, acid chlorides, and acid anhydrides.
- Waste Disposal It is inappropriate and possibly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quantities of expired or waste pharmaceuticals may be mixed with wet cat litter or coffee grounds, double-bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged, and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator
Premarin Preparation Products And Raw materials
Raw materials
Preparation Products
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12126-59-9, PremarinRelated Search:
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- Steroids
- 杂质对照品
- 化学试剂
- 甾体激素类
- 医药与生物化工
- 激素及有关药物
- C18H19NaO5S
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- 马烯雌酮杂质7
- 结合雌激素
- 甲羟孕酮
- 混合雌激素
- 共轭雌激素
- 12126-59-9
- HSDB 3076
- Conjugated Estrogen sodium
- Equilin Impurity 7
- Premarin USP/EP/BP
- Climarest
- Ccris 7207
- Azumon
- Ayerogen crema vaginal
- Ayerogen
- Sodium equilin sulfate
- Sodium [(9S,13S,14S)-13-methyl-17-oxo-9,11,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-yl] sulfate
- Premarin
- EQUINEOESTROGEN
- CONJUGATEDESTROGENS,USP
- Methypregnone