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5-HYDROXYINDOLE-3-ACETIC ACID

5-HYDROXYINDOLE-3-ACETIC ACID Structure
5-HYDROXYINDOLE-3-ACETIC ACID
  • CAS No.54-16-0
  • Chemical Name:5-HYDROXYINDOLE-3-ACETIC ACID
  • CBNumber:CB0362913
  • Molecular Formula:C10H9NO3
  • Formula Weight:191.18
  • MOL File:54-16-0.mol
5-HYDROXYINDOLE-3-ACETIC ACID Property
  • Melting point 161-164 °C (dec.) (lit.)
  • Boiling point 326.92°C (rough estimate)
  • Density 1.2722 (rough estimate)
  • refractive index 1.5310 (estimate)
  • storage temp. -20°C
  • solubility Soluble in ethanol (50 mg/ml).
  • pka 4.54±0.30(Predicted)
  • form crystalline
  • color off-white to purple
  • Sensitive Light Sensitive
  • BRN 168797
  • Stability Air Sensitive, Light Sensitive
  • InChIKey DUUGKQCEGZLZNO-UHFFFAOYSA-N
  • CAS DataBase Reference 54-16-0
  • EWG's Food Scores 1
  • NCI Dictionary of Cancer Terms 5-hydroxyindoleacetic acid
  • FDA UNII YHC763JY1P
  • UNSPSC Code 41116107
  • NACRES NA.77
Safety
  • Safety Statements  :22-24/25
  • WGK Germany  :3
  • RTECS  :NL3650000
  • F  :8-10-23
  • HS Code  :29339980
  • NFPA 704:
    1
    1 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P271-P280
5-HYDROXYINDOLE-3-ACETIC ACID Price More Price(7)
  • Brand: Sigma-Aldrich(India)
  • Product number: H8876
  • Product name : 5-Hydroxyindole-3-acetic acid
  • Purity: ≥98% (HPLC), crystalline
  • Packaging: 100MG
  • Price: ₹3420.7
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: H8876
  • Product name : 5-Hydroxyindole-3-acetic acid
  • Purity: ≥98% (HPLC), crystalline
  • Packaging: 500MG
  • Price: ₹10489.43
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: H8876
  • Product name : 5-Hydroxyindole-3-acetic acid
  • Purity: ≥98% (HPLC), crystalline
  • Packaging: 1G
  • Price: ₹17428.25
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: ALFA India
  • Product number: ALF-J61435-ME
  • Product name : 5-Hydroxyindole-3-acetic acid, 98%
  • Purity: 
  • Packaging: 500mg
  • Price: ₹2708
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: H0355
  • Product name : 5-Hydroxyindole-3-acetic Acid
  • Purity: 
  • Packaging: 100MG
  • Price: ₹3100
  • Updated: 2022/05/26
  • Buy: Buy

5-HYDROXYINDOLE-3-ACETIC ACID Chemical Properties,Usage,Production

  • Description 5-hydroxy Indole-3-acetic acid (5-HIAA) is the primary metabolite of serotonin (5-HT; ). It is formed when 5-HT is metabolized by monamine oxidase and aldehyde dehydrogenase in the liver. 5-HIAA is excreted in urine and has been used as a biomarker for detection of neuroendocrine tumors and an internal standard for the quantification of serotonin metabolism in rat brain using mass spectrometry. 5-HIAA has also been associated with autism, insomnia, and chronic migraine.
  • Chemical Properties beige crystalline powder
  • Uses 5-Hydroxyindole-3-acetic acid is a major serotonin metabolite.
  • Uses 5-Hydroxyindole-3-acetic acid is an impurity of chlorpheniramine (C424300), an antihistaminic agent.
  • Definition ChEBI: A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
  • General Description 5-Hydroxyindole-3-acetic acid (5-HIAA) is the catabolic end product of serotonin pathway. 5-HIAA is present in body fluids like cerebrospinal fluid (CSF), blood and urine. The expression levels of 5-HIAA is different among the normal and cancer patients. Sepiapterin reductase deficiency results in low level of 5-HIAA in CSF. 5-HIAA level is low in CSF in patients with bipolar 1 disorder with childhood attention-deficit hyperactivity disorder (ADHD).
  • Mechanism of action The primary product of the metabolism of serotonin. Formed by the oxidative deamination of serotonin by monoamine oxidase, presumably the A isozyme, 5-HIAA is subsequently cleared by an active transport mechanism. Unlike serotonin, 5-HIAA is not a neurotransmitter and thus its formation contributes to the termination of the synaptic actions of serotonin. Inhibition of monoamine oxidase activity enhances and prolongs the actions of serotonin.
5-HYDROXYINDOLE-3-ACETIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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5-HYDROXYINDOLE-3-ACETIC ACID Spectrum
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  • 5-羟基吲哚酸(5-HIAA)
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  • 5-HIAA, 5-羟基吲哚-3-乙酸
  • 54-16-0
  • 5-Hydroxyindole-3-acetic acid (5-HIAA) solution
  • 5-HYDROXYINDOLE-3-ACETIC ACID, 10 mM in DMSO
  • 5-Hydroxyindole-3-acetic acid in methanol
  • -Hydroxyindole-3-acetic acid
  • 5&＃039
  • inhibit,5HYDROXYINDOLE3ACETIC ACID,Inhibitor,Endogenous Metabolite,5 HYDROXYINDOLE 3 ACETIC ACID
  • 2H5]-5-Hydroxyindoleacetic acid
  • HIAA
  • 5-HIAA
  • 5-HYDROXY-3-INDOLEACETIC ACID
  • 5-oxyindoleaceticacid
  • 2-(5-hydroxy-1H-indol-3-yl)acetic acid
  • (5-hydroxyindol-3-yl)aceticaci

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