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PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE

PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Structure
PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE
  • CAS No.207671-42-9
  • Chemical Name:PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE
  • CBNumber:CB0356837
  • Molecular Formula:C7H7NO5
  • Formula Weight:185.13
  • MOL File:207671-42-9.mol
PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Property
  • Melting point 246-248 °C (dec.)(lit.)
  • storage temp. Store at -20°C
  • solubility DMSO: 1.4 mg/ml; PBS (pH 7.2): 0.2 mg/ml
  • form A crystalline solid
  • BRN 131631
  • UNSPSC Code 12352100
  • NACRES NA.22
Safety
  • Hazard Codes  :Xi
  • Risk Statements  :36/37/38
  • Safety Statements  :26
  • WGK Germany  :3
  • NFPA 704:
    0
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P302+P352-P305+P351+P338
PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: P63395
  • Product name : 2,4-Pyridinedicarboxylic acid monohydrate
  • Purity: 98%
  • Packaging: 5G
  • Price: ₹3453.18
  • Updated: 2022/06/14
  • Buy: Buy

PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Chemical Properties,Usage,Production

  • Description 2,4-Pyridinedicarboxylic Acid (2,4-PDCA) is a compound that structurally mimics 2-oxoglutarate (2-OG, also known as α-ketoglutarate) and chelates zinc, thus affecting a range of enzymes. As a 2-OG mimic, it blocks the activity of 2-OG oxygenases, which include certain lysine demethylases and a variety of hydroxylases (e.g., prolyl, collagen, lysyl). 2,4-PDCA inhibits several Jumonji domain-containing lysine demethylases when used at low micromolar concentrations. Through its effects on hydroxylases, including prolyl hydroxlase 1 (IC50 = 1.5 μM), 2,4-PDCA modulates hypoxia-inducible factor turnover, collagen synthesis, and plant cell wall formation. It can inhibit zinc-dependent enzymes, like metallo-β-lactamase. 2,4-PDCA also affects and is translocated by organic anion transporters.
PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Preparation Products And Raw materials
Raw materials
Preparation Products
PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Suppliers
Global(52)Suppliers
  • Supplier：
    Career Henan Chemica Co
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  • Supplier： BOC Sciences
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  • Country：United States
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PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Spectrum
207671-42-9, PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATERelated Search:
  • Pyridines
  • Heterocyclic Building Blocks
  • C7 and C8
  • Heterocyclic Building Blocks
  • Chemical Synthesis
  • C7
  • Building Blocks
  • 有机中间体
  • 化学连接
  • 杂环化合物
  • Pyridines
  • Heterocyclic Building Blocks
  • C7 and C8
  • Building Blocks
  • C7H5NO4H2O
  • 2,4-吡啶二羧酸 一水合物
  • 2,4-吡啶二羧酸一水合物(吡啶-2,4-二羧酸单水合物、吡啶-2,4-二羧酸水合物、2,4-吡啶二甲酸水合物)
  • 207671-42-9
  • 2,4-Pyridinedicarboxylic acid Monohydrate 98%
  • 2,4-Pyridinedicarboxylicacid, hydrate (1:1)
  • LUTIDINIC ACID MONOHYDRATE
  • PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE
  • 2,4-PYRIDINECARBOXYLIC ACID MONOHYDRATE
  • 2,4-PYRIDINEDICARBOXYLIC ACID MONOHYDRATE
  • PYRIDINE-2,4-DICARBOXYLIC ACID HYDRATE

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