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Azido-PEG1-NHS ester

Azido-PEG1-NHS ester Structure
Azido-PEG1-NHS ester
  • CAS No.1807530-06-8
  • Chemical Name:Azido-PEG1-NHS ester
  • CBNumber:CB03062340
  • Molecular Formula:C9H12N4O5
  • Formula Weight:256.22
  • MOL File:1807530-06-8.mol
Azido-PEG1-NHS ester Property
  • solubility Soluble in DMSO, DCM, DMF
  • form Liquid
  • color Colorless to light yellow
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Azido-PEG1-NHS ester Chemical Properties,Usage,Production

  • Description Azido-PEG1-NHS ester is a click chemistry PEG reagent with broad application. Azide(N3) group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
  • Uses Azido-PEG1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG1-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
  • IC 50 PEGs; Alkyl/ether
  • References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG1-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
Azido-PEG1-NHS ester Suppliers
Global(36)Suppliers
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
  • Country：United States
  • ProdList：32159
  • Advantage：58
  • Supplier：
    Nextpeptide Inc
  • Tel：+86-0571-81612335<br/>+8613336028439
  • Email：sales@nextpeptide.com
  • Country：China
  • ProdList：19908
  • Advantage：58
Azido-PEG1-NHS ester Spectrum
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