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tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate

tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate Structure
tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate
  • CAS No.1256584-75-4
  • Chemical Name:tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate
  • CBNumber:CB02624336
  • Molecular Formula:C25H27IN2O2
  • Formula Weight:514.4
  • MOL File:1256584-75-4.mol
tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate Property
  • Boiling point 609.3±55.0 °C(Predicted)
  • Density 1.43±0.1 g/cm3(Predicted)
  • pka 14.00±0.30(Predicted)
  • InChI InChI=1S/C25H27IN2O2/c1-7-16-9-10-17(13-19(16)26)25(5,6)22-21(23(29)30-24(2,3)4)18-11-8-15(14-27)12-20(18)28-22/h8-13,28H,7H2,1-6H3
  • InChIKey QJJFMODIDDQXRV-UHFFFAOYSA-N
  • SMILES N1C2=C(C=CC(C#N)=C2)C(C(OC(C)(C)C)=O)=C1C(C1=CC=C(CC)C(I)=C1)(C)C
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate Chemical Properties,Usage,Production

  • Uses tert-?Butyl 6-?Cyano-?2-?(2-?(4-?ethyl-?3-?iodophenyl)?propan-?2-?yl)?-?1H-?indole-?3-?carboxylate is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth.
tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate Preparation Products And Raw materials
Raw materials
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tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate Suppliers
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tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate Spectrum
1256584-75-4, tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylateRelated Search:
  • 1256584-75-4
  • 化学品
  • 化学试剂
  • 化工原料及中间体
  • 替尼类抗癌药物中间体
  • 中间体-中间体
  • 125684-75-4
  • 阿来替尼杂质7
  • 6-氰基-2-(2-(2-(4-乙基-3-碘苯基)丙-2-基)-1H-吲哚-3-羧酸叔丁酯
  • 6-氰基-2-[2-(4-乙基-3-碘苯基)丙-2-基]-1H-吲哚-3-甲酸叔丁酯
  • 2-(2-(4-乙基-3-碘)丙烷-2-基)-6-氰基-1H-吲哚-3-羧酸特丁酯
  • 阿来替尼中间体B
  • 6-氰基-2-[1-(4-乙基-3-碘苯基)-1-甲基乙基]-1H-吲哚-3-羧酸叔丁酯
  • 6-氰基-2-(2-(4-乙基-3-碘苯基)丙烷-2-基)-1H-吲哚-3-羧酸叔丁酯
  • 叔-丁基6-氰基-2-(2-(4-乙基-3-碘苯基)丙-2-基)-1H-吲哚-3-羧酸酯/2
  • 阿来替尼中间体II
  • 叔-丁基6-氰基-2-(2-(4-乙基-3-碘苯基)丙-2-基)-1H-吲哚-3-羧酸酯
  • 6-氰基-2-(2-(4-乙基-3-碘苯基)丙-2-基)-1H-吲哚-3-羧酸叔丁酯
  • 艾乐替尼中间体
  • 艾乐替尼中间体2
  • 艾乐替尼中间体B
  • 1256584-75-4
  • Aletinib impurity 7
  • tert-butyl 2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-6-isocyano-1H-indole-3-carboxylate
  • Alectinib intermediate I
  • tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1...
  • Alectinib intermediate II
  • Alectinib intermediate B
  • 1H-Indole-3-carboxylic acid, 6-cyano-2-[1-(4-ethyl-3-iodophenyl)-1-methylethyl]-, 1,1-dimethylethyl ester
  • tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate/tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate
  • TERT-BUTYL 6-CYANO-2- (2-(4-ETHYL-3-IODOPHENYL)PROPAN-2-YL) -1H-INDOLE-3-CARBOXYLATE _ 1256584-75-4
  • Alectinib Impurity 6
  • 6-Cyano-2-[1-(4-ethyl-3-iodophenyl)-1-methylethyl]-1H-indole-3-carboxylic acid 1,1-dimethylethyl ester
  • 2-Methyl-2-propanyl 6-cyano-2-[2-(4-ethyl-3-iodophenyl)-2-propany l]-1H-indole-3-carboxylate
  • 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate
  • tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate-10
  • tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate

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