ChemicalBook > CAS DataBase List > 4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]-

4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]-

4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]- Structure
4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]-
  • CAS No.314771-88-5
  • Chemical Name:4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]-
  • CBNumber:CB02602866
  • Molecular Formula:C18H14ClFN4O4
  • Formula Weight:404.78
  • MOL File:314771-88-5.mol
4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]- Property
  • Boiling point 585.0±50.0 °C(Predicted)
  • Density 1.534±0.06 g/cm3(Predicted)
  • storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
  • pka 5.07±0.70(Predicted)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302
  • Precautionary statements P280-P305+P351+P338

4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]- Chemical Properties,Usage,Production

  • Uses (S)-N-(3-chloro-4-fluorophenyl)-6-nitro-7-(tetrahydrofuran-3-yloxy)quinazolin-4-amine is a used in the synthetic preparation of 4-anilinoquinazolines with C-6 urea-linked side chains as inhibitors of epidermal growth factor receptor. It is also used in the preparation of (2Z)-Afatinib (A355305) which is used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.
4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]- Preparation Products And Raw materials
Raw materials
Preparation Products
4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]- Suppliers
Global(176)Suppliers
  • Supplier：
    career henan chemical co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：sales@coreychem.com
  • Country：China
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  • Supplier：
    career henan chemical co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：factory@coreychem.com
  • Country：China
  • ProdList：29808
  • Advantage：58
  • Supplier：
    Fuxin Pharmaceutical
  • Tel：+86-021-021-50872116<br/>+8613122107989
  • Email：contact@fuxinpharm.com
  • Country：China
  • ProdList：10035
  • Advantage：58
4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]- Spectrum
314771-88-5, 4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]-Related Search:
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  • C18H14ClFN4O4
  • (S)-N-(3-氯-4-氟苯基)-6-硝基-7-((四氢呋喃-3-基)氧基)喹唑啉-4-胺(阿法替尼杂质)
  • 化合物 (S)-N-(3-CHLORO-4-FLUOROPHENYL)-6-NITRO-7-((TETRAHYDROFURAN-3-YL)OXY)QUINAZOLIN-4-AMINE
  • N-(3-氯-4-氟苯基)-6-硝基-7-[[(3S)-四氢-3-呋喃基]氧基]-4-喹唑啉胺N-(3-CHLORO-4-FLUOROPHENYL)-6-NITRO-7-[(3S)-OXOLAN-3-YL] OXYQUINAZOLIN-4-AMINE
  • 不确定性A
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  • 阿法替尼硝基物 4-[(3-氯-4-氟苯基)氨基]-6-硝基-7-((S)-四氢呋喃-3-基氧基)-喹唑啉
  • 阿法替尼硝基物
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  • 4-[(3-氯-4-氟苯基)氨基]-6-硝基-7-((S)-四氢呋喃-3-基氧基)-喹唑啉(阿法替尼中间体) 500G
  • (S)-N-(3-氯-4-氟苯基)-6-硝基-7-[(四氢-3-呋喃基)氧基]喹唑啉-4-胺
  • 4-[(3-氯-4-氟苯基)氨基]-6-硝基-7-((S)-四氢呋喃-3-基氧基)-
  • 4-[(3-氯-4-氟苯基)氨基]-6-硝基-7-((S)-四氢呋喃-3-基氧基)-喹唑啉(中5)
  • N-(3-氯-4-氟苯基)-6-硝基-7-[[(3S)-四氢...
  • 314771-88-5
  • (S)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine(AfatinibImpurity)
  • 7-((S)-tetrahydrofuran-3-yloxy)-4-(3-chloro-4-fluorophenyl)a...
  • 7-((S)-tetrahydrofuran-3-yloxy) -N-(3-chloro-4-fluorophenyl) -6-nitroquinazolin-4-amine
  • N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]-
  • N-(3-chloro-4-fluorophenyl)-6-nitro-7-[(3S)-oxolan-3-yl]oxyquinazolin-4-amine
  • N-(3-chloro-4-fluorophenyl)-6-nitro-7-[(3S)-oxolan-3-yl]oxyquinazolin-
  • N-(3-Chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]
  • (S)-N-(3-chloro-4-fluorophenyl)-6-nitro-7-(tetrahydrofuran-3-yloxy)quinazolin-4-aMine
  • 4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]-
  • Afatinib intermediate C
  • N-(3-Chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4-quinazolinaMine
  • 7-((S)-tetrahydrofuran-3-yloxy)-4-(3-chloro-4-fluorophenyl)aMino-6-nitroquinazoline

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