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XL147

XL147 Structure
XL147
  • CAS No.956958-53-5
  • Chemical Name:XL147
  • CBNumber:CB02512204
  • Molecular Formula:C21H16N6O2S2
  • Formula Weight:448.52
  • MOL File:956958-53-5.mol
XL147 Property
  • Boiling point 638.9±65.0 °C(Predicted)
  • Density 1.538
  • storage temp. Store at -20°C
  • solubility ≥22.45 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH
  • form solid
  • pka 6.71±0.30(Predicted)
  • color Light brown to brown
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302
  • Precautionary statements P264-P270-P301+P312-P330-P501

XL147 Chemical Properties,Usage,Production

  • Description XL147 analog is an analog of XL147 .
  • Uses XL147 analogue is one of Pyrimidine derivatives as JAK-2 inhibitors in combination with other agents and their use in the treatment of diseases.
  • Definition ChEBI: XL147 is a sulfonamide that is the N-4-toluenesulfonyl (N-tosyl) derivative of N-(2,1,3-benzothiadiazol-5-yl)quinoxaline-2,3-diamine. A selective PI3K inhibitor used in cancer treatment. It has a role as an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor and an antineoplastic agent. It is a sulfonamide, a quinoxaline derivative, a benzothiadiazole and an aromatic amine.
  • target PI3Kα
  • IC 50 PI3K-alpha
XL147 Preparation Products And Raw materials
Raw materials
Preparation Products
XL147 Suppliers
Global(155)Suppliers
  • Supplier：
    Capot Chemical Co.,Ltd.
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    BOC Sciences
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  • Email：marketing@targetmol.com
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XL147 Spectrum
956958-53-5, XL147Related Search:
  • Sulfur & Selenium Compounds
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Heterocycles
  • Aromatics
  • Amines
  • Inhibitors
  • PI3K
  • mTOR
  • Akt
  • 抑制剂
  • 生物试剂
  • 合成有机化合物配体
  • 细胞生物学试剂
  • 小分子抑制剂，天然产物
  • 小分子抑制剂
  • 化合物XL147 ANALOGUE,10 MM DMSO 溶液
  • PILARALISIB类似物
  • XL147,PI3K抑制剂
  • 奎宁树
  • N-[3-CHEMICALBOOK(苯并[C][1,2,5]噻二唑-5-基氨基)喹喔啉-2-基]-4-甲基苯磺酰胺
  • PI3KS抑制剂(XL147)
  • XL147 类似物
  • N-[3-(苯并[C][1,2,5]噻二唑-5-基氨基)喹喔啉-2-基]-4-甲基苯磺酰胺
  • N-[3-(2,1,3-苯并噻二唑-5-氨基)-2-喹喔啉基]-4-甲基苯磺酰胺
  • 956958-53-5
  • Pilaralisib analogue, 10 mM in DMSO
  • XL147 analog XL-147
  • 9S)-Cinchonine
  • Pilaralisib analog (XL147 analog, SAR245408 analog)
  • XL147 USP/EP/BP
  • CS-36
  • Benzenesulfonamide, N-[3-(2,1,3-benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methyl-
  • XL147 ANALOG
  • N-[3-(2,1,3-Benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methylbenzenesulfonamide XL 147
  • PI3K inhibitorX
  • XL-147(SAR245408)
  • XL147
  • N-[3-(2,1,3-Benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methylbenzenesulfonamide,
  • N-[3-(Benzo[c][1,2,5]thiadiazol-5-ylaMino)quinoxalin-2-yl]-4-MethylbenzenesulfonaMide
  • XL147;XL-147;SAR245408
  • SAR245408
  • <br>N-(3-(Benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenes ulfonamide
  • XL147, >=98%
  • XL147 ANALOG 1G
  • N-[3-(2,1,3-benzothiadiazol-5-ylamino)quinoxalin-2-yl]-4-methylbenzenesulfonamide
  • XL147;XL 147
  • XL147 analogue(PI3K inhibitor X)
  • SAR245408 (XL-147)
  • XL147 analogue

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