ChemicalBook > CAS DataBase List > MOPS

MOPS

Description application Reference

MOPS

CAS No.1132-61-2
Chemical Name:MOPS
CBNumber:CB0221586
Molecular Formula:C7H15NO4S
Formula Weight:209.26
MOL File:1132-61-2.mol

MOPS Property

Melting point 277-282 °C
Density 1.3168 (rough estimate)
bulk density 350kg/m3
vapor pressure 0Pa at 25℃
refractive index 1.6370 (estimate)
Flash point 116 °C
storage temp. room temp
solubility H₂O: 1 M at 20 °C, clear
form Powder/Solid
color White
PH 2.5-4.0 (25℃, 1M in H2O)
pka 7.2(at 25℃)
PH Range 6.5 - 7.9
Odor Odorless
biological source synthetic
Water Solubility 1000 g/L (20 ºC)
λmax λ: 260 nm Amax: 0.020
λ: 280 nm Amax: 0.015
Merck 14,6265
BRN 1106776
Stability Stable. Incompatible with strong bases, strong oxidizing agents.
InChIKey DVLFYONBTKHTER-UHFFFAOYSA-N
LogP -2.94 at 20℃
CAS DataBase Reference 1132-61-2(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 273BP63NV3
EPA Substance Registry System 4-Morpholinepropanesulfonic acid (1132-61-2)
Absorption ≤0.05 at 260nm
≤0.05 at 280nm
UNSPSC Code 12352200
NACRES NA.25

Safety

Hazard Codes :Xi
Risk Statements :36/37/38
Safety Statements :26-36
WGK Germany :1
RTECS :QE9104530
TSCA :Yes
HS Code :29349990

NFPA 704:

	1
1		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319-H335
Precautionary statements P261-P305+P351+P338-P280a-P304+P340-P405-P501a

MOPS Price More Price(32)

Brand: Sigma-Aldrich(India)
Product number: RDD003
Product name : MOPS
Purity: anhydrous, free-flowing, Redi-Dri?, ≥99.5%
Packaging: 1KG
Price: ₹54666.25
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: RDD003
Product name : MOPS
Purity: anhydrous, free-flowing, Redi-Dri?, ≥99.5%
Packaging: 2.5KG
Price: ₹84326.75
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: M5162
Product name : MOPS
Purity: BioXtra, ≥99.5% (titration)
Packaging: 25G
Price: ₹8443.5
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: M3183
Product name : MOPS
Purity: BioPerformance Certified, suitable for cell culture, ≥99.5% (titration)
Packaging: 25G
Price: ₹5358.38
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: M3183
Product name : MOPS
Purity: BioPerformance Certified, suitable for cell culture, ≥99.5% (titration)
Packaging: 100G
Price: ₹12091.53
Updated: 2022/06/14
Buy: Buy

MOPS Chemical Properties,Usage,Production

Description MOPS (3-morpholinopropanesulfonic acid) is a buffer introduced by Good et al. in the 1960s. It is a structural analog to MES. Its chemical structure contains a morpholine ring. HEPES is a similar pH buffering compound that contains a piperazine ring. With a pKa of 7.20, MOPS is an excellent buffer for many biological systems at near-neutral pH.It is used as a synthetic buffering agent below pH 7.5.
application MOPS is frequently used as a buffering agent in biology and biochemistry. It has been tested and recommended for polyacrylamide gel electrophoresis. Usage above 20 mM in mammalian cell culture work is not recommended. MOPS buffer solutions become discolored (yellow) over time, but reportedly slight discoloration does not significantly affect the buffering characteristics.
Reference P. H. Quail, D. Marme, E. Schäfer, Particle-bound phytochrome from maize and pumpkin, Nature New Biology, 1973, vol. 245, pp. 189-191
Chemical Properties White/clear crystalline powder
Uses MOPS acts as a multi-purpose buffering agent used in various biological research.
Uses Due to its inert nature, 3-morpholinopropanesulfonic acid (MOPS) is widely used as a buffer in many biochemical studies. MOPS has been used as a cell culture additive component in lentiviral particle production, a buffering agent in microbial growth medium and nuclei extraction buffer, a component of Roswell Park Memorial Institute (RPMI) medium for diluting fungal inoculum, and a buffer in capillary-zone electrophoresis to test performance. It is also used for the dilution of proteins from algal samples.
Definition ChEBI: 3-(N-morpholino)propanesulfonic acid is a Good's buffer substance, pKa = 7.2 at 20 ℃. It is a member of morpholines, a MOPS and an organosulfonic acid. It is a conjugate acid of a 3-(N-morpholino)propanesulfonate. It is a tautomer of a 3-(N-morpholiniumyl)propanesulfonate.
General Description 3-(N-Morpholino)propane sulfonic acid (MOPS) is an N-substituted amino sulfonic acid with a morpholinic ring. MOPS is capable of buffering within a pH range of 6.5-7.9. MOPS is widely used in biological and biochemical studies due to its inert properties. It does not interact with any metal ions in solutions and has significant metal-buffer stability especially with copper (Cu), nickel (Ni), manganese (Mn), zinc (Zn), cobalt (Co) ions. MOPS buffer maintains the pH of the mammalian cell culture medium. MOPS functions to maintain pH in denaturing gel electrophoresis of RNA. MOPS can modify lipid interactions and influence the thickness and barrier properties of membranes. MOPS interacts with bovine serum albumin and stabilizes the protein. Hydrogen peroxide oxidizes MOPS slowly to N-oxide form.
Flammability and Explosibility Not classified
Synthesis Morpholine and 1,3-Propanesultone are added to absolute ethanol for reaction. The crude product synthesized is purified to obtain 3-Morpholinopropanesulfonic acid.