ChemicalBook > CAS DataBase List > 4-(Hydroxyamino)-4-oxobutanoic acid
4-(Hydroxyamino)-4-oxobutanoic acid
- CAS No.4743-99-1
- Chemical Name:4-(Hydroxyamino)-4-oxobutanoic acid
- CBNumber:CB02174169
- Molecular Formula:C4H7NO4
- Formula Weight:133.1
- MOL File:4743-99-1.mol
4-(Hydroxyamino)-4-oxobutanoic acid Property
- Melting point 82-86 °C(Solv: acetonitrile (75-05-8))
- Density 1.436±0.06 g/cm3(Predicted)
- storage temp. Inert atmosphere,Store in freezer, under -20°C
- pka 5.28±0.10(Predicted)
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H315-H319-H335
- Precautionary statements P261-P305+P351+P338
4-(Hydroxyamino)-4-oxobutanoic acid Chemical Properties,Usage,Production
-
Preparation
To a refluxing solution of 5.0 gm (0.05 mole) of succinic anhydride in 100 ml of benzene is added a solution of 6.3 gm (0.05 mole) of O-ben- zylhydroxylamine in 20 ml of benzene. As soon as the addition has been completed, the reaction mixture is cooled, and the precipitated product is separated. Upon recrystallization from a benzene-methyl ethyl ketone mixture, 7.6 gm (68.2%) of N-benzyloxysuccinamic acid, m.p. 95-96°C isolated.
A suspension of 4.3 gm (0.0193 mole) of this intermediate and a stron- tium carbonate catalyst containing 5% palladium in methyl ethyl ketone is hydrogenated. Upon working up the reaction mixture, 1.45 gm (56.7%) of succinomonohydroxamic acid, m.p. 95-96°C is isolated.
4-(Hydroxyamino)-4-oxobutanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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