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FR 139317

FR 139317 Structure
FR 139317
  • CAS No.142375-60-8
  • Chemical Name:FR 139317
  • CBNumber:CB0216568
  • Molecular Formula:C33H44N6O5
  • Formula Weight:604.74
  • MOL File:142375-60-8.mol
FR 139317 Property
  • Boiling point 943.9±65.0 °C(Predicted)
  • Density 1.27±0.1 g/cm3(Predicted)
  • storage temp. Desiccate at +4°C
  • solubility Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO
  • form Powder
  • pka 2.68±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

FR 139317 Chemical Properties,Usage,Production

  • Uses FR 139317 is a novel, potent endothelin ETA receptor antagonist.
  • Biological Activity A highly potent and selective ET A endothelin receptor antagonist (K i values are 1 nM and 7.3 μ M at ET A and ET B subtypes respectively). Active in vivo .
  • IC 50 ETA
FR 139317 Preparation Products And Raw materials
Raw materials
Preparation Products
FR 139317 Suppliers
Global(44)Suppliers
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    TargetMol Chemicals Inc.
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FR 139317 Spectrum
142375-60-8, FR 139317Related Search:
  • 抑制剂
  • 合成有机化合物配体
  • C33H44N6O5
  • FR 139317,ETA RECEPTOR拮抗剂
  • 化合物 FR 139317
  • N-[(六氢-1H-氮杂卓-1-基)羰基]-L-亮氨酰-1-甲基-D-色氨酰-3-(2-吡啶基)-D-丙氨酸
  • FR 139317,竞争性的ET A受体拮抗剂
  • 化合物 T22791
  • 142375-60-8
  • (2R)-2-[[(2R)-2-([(2S)-2-[(1-AZEPANYLCARBONYL)AMINO]-4-METHYLPENTANOYL]AMINO)-3-(1-METHYL-1H-INDOL-3-YL)PROPANOYL]AMINO]-3-(2-PYRIDINYL)PROPANOIC ACID
  • FR 139317, ETA receptor antagonist
  • (2R)-2-[[(2R)-2-[[(2S)-2-(AZEPANE-1-CARBONYLAMINO)-4-METHYLPENTANOYL]AMINO]-3-(1-METHYLINDOL-3-YL)PROPANOYL]AMINO]-3-PYRIDIN-2-YLPROPANOIC ACID
  • FR139317,CID107810
  • N,N-hexamethylenecarbamoyl-leu-N-*methyl-D-trp-D-
  • (N,N-HEXAMETHYLENE) CARBAMOYL-LEU-D-TRP(N-ME)-D-2-PYA
  • N-[N-[N-[(HEXAHYDRO-1H-AZEPIN-1-YL)CARBONYL]-L-LEUCYL]-1-METHYL-D-TRYPTOPHYL]-3-(2-PYRIDINYL)-D-ALANINE
  • D-Alanine, N-(N-(N-((hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl)-1-methyl-D-tryptophyl)-3-(2-pyridinyl)-
  • D-Alanine, N-((hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl-1-methyl-D-tryptophyl-3-(2-pyridinyl)-
  • 2-((1-(Hexahydro-1H-azepinyl)carbonyl)amino-4-methylpentanoyl)-3-(-(1-methyl-1H-indolyl)propionyl)amino-3-(2-pyridyl)propionic acid
  • (HEXAHYDRO-1H-AZEPINYL)CARBONYL-LEU-DTRP(ME)-D-ALA(2-PYRIDYL)-OH
  • (HEXAHYDRO-1H-AZEPINYL)CARBONYL-LEU-D-(1-ME)-TRP-DPAL
  • FR 139317

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