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4-Methyl-2-hexanamine hydrochloride

CAS No.13803-74-2
Chemical Name:4-Methyl-2-hexanamine hydrochloride
CBNumber:CB01476978
Molecular Formula:C7H18ClN
Formula Weight:151.68
MOL File:13803-74-2.mol

4-Methyl-2-hexanamine hydrochloride Property

Melting point 128.0 to 132.0 °C
Flash point 9℃
storage temp. room temp
solubility H2O: soluble5mg/mL (clear solution)
form powder
color white to beige
Water Solubility H2O: 5mg/mL (clear solution)
InChI InChI=1S/C7H17N.ClH/c1-4-6(2)5-7(3)8;/h6-7H,4-5,8H2,1-3H3;1H
InChIKey ZKKBPHUAHARETG-UHFFFAOYSA-N
SMILES C(C)(CC)CC(N)C.Cl
CAS DataBase Reference 13803-74-2(CAS DataBase Reference)
UNSPSC Code 41116107
NACRES NA.77

Safety

Hazard Codes :Xn,T,F
Risk Statements :22-36/37/38-39/23/24/25-23/24/25-11
Safety Statements :26-45-36/37-16-7
RIDADR :UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany :3
HS Code :2921199990

NFPA 704:

	0
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H302-H315-H319-H335
Precautionary statements P261-P264-P270-P301+P312-P302+P352-P305+P351+P338

4-Methyl-2-hexanamine hydrochloride Price More Price(6)

Brand: Sigma-Aldrich(India)
Product number: SML0460
Product name : Methylhexanamine hydrochloride
Purity: ≥98% (HPLC)
Packaging: 10MG
Price: ₹9277.03
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: SML0460
Product name : Methylhexanamine hydrochloride
Purity: ≥98% (HPLC)
Packaging: 50MG
Price: ₹37357.08
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: M-157
Product name : Methylhexanamine hydrochloride solution
Purity: 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
Packaging: 1ML
Price: ₹13401.35
Updated: 2022/06/14
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Brand: TCI Chemicals (India)
Product number: M2409
Product name : 4-Methyl-2-hexylamine Hydrochloride
Purity:
Packaging: 1G
Price: ₹2000
Updated: 2022/05/26
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Brand: TCI Chemicals (India)
Product number: M2409
Product name : 4-Methyl-2-hexylamine Hydrochloride
Purity:
Packaging: 5G
Price: ₹2900
Updated: 2022/05/26
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4-Methyl-2-hexanamine hydrochloride Chemical Properties,Usage,Production

Description 1,3-Dimethylpentylamine is a pseudo-adrenergic drug introduced by Lilly Company in the United States in the mid-1940s under the trade name Forthane. 1,3-dimethylpentylamine and its hydrochloride have obvious curative effects in the treatment of nasal congestion and gingival hyperplasia, and are much less stimulating to the mind than pseudoephedrine and amphetamine, and their unique pharmacological advantages cause attached great importance to the experts.
Chemical Properties White Solid
Uses 1,3-Dimethylpentylamine is useful in composition in treating hypertrophied and hyperplastic gums which showed a significant reduction in swelling.
Uses Methylhexanamine (hydrochloride) is a simple aliphatic amine that was once marketed as a nasal decongestant (Forthane) but is now sold as a bodybuilding supplement (Floradrene, Geranamine). It is also sold as a mild stimulant in the form of party pills and has been reported to cause cerebral hemorrhage in a case report. While little is known about its mode of action, methylhexanamine interferes in immunoassays for amphetamines, presumably because of the common ethylamine structure. This compound is intended for forensic or research purposes.[Cayman Chemical]
General Description 4-Methyl-2-hexanamine hydrochloride is a psychoactive substance and has been found to be an inhibitor of serotonin uptake, which may be related to its ability to inhibit the function of the serotonin transporter. The amount of 4-methyl-2-hexanamine hydrochloride absorbed by the body varies depending on how it is taken. When taken orally, 4-methyl-2-hexanamine hydrochloride enters through the digestive tract and reaches high levels in the blood stream. When taken intravenously, it enters the bloodstream directly and can reach higher concentrations in the blood. When inhaled, 4-methyl-2-hexanamine hydrochloride can enter into the lungs at high concentrations and then is absorbed into the bloodstream. 4-Methyl-2-hexanamine hydrochloride also degrades quickly in natural environments due to its biodegradable properties.
Biochem/physiol Actions Methylhexanamine is a naturally substance isolated from Pelargonium graveolen. It is a component of geranium oil. Methylhexanamine is a sympathomimentic that increase levels of norepinephrine in the synaptic cleft.
Synthesis At room temperature, 800 mL absolute ethanol was added into a 2 L three neck flask, stirred, and 35.38 g (1.538 mol) of metal sodium was added in batches to obtain a colorless transparent liquid. Cool slightly, add 200g (1.537 rnol) of ethyl acetoacetate, continue heating slowly, and add 232g (1.693 mol) of 2-bromobutane drop under weak reflux. Continue heating and react for 8 h at 80~84 ??. Stop heating, cool naturally to room temperature, leave it still, filter by suction, and concentrate the yellow green filtrate under reduced pressure to obtain 241.4 g of 1,3-Dimethylpentanamine Hydrochloride with light yellow viscous solid in 84.3% yield.