Acth (6-24)
- Product NameActh (6-24)
- CAS33512-65-1
- CBNumberCB01367195
- MFC111H175N35O21
- MW2335.8
- MOL File33512-65-1.mol
Chemical Properties
| Density | 1.45±0.1 g/cm3(Predicted) |
| Sequence | His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro |
Acth (6-24) Chemical Properties,Usage,Production
Uses
ACTH (6-24) (human) (Adrenocorticotropic hormone (6-24)) is an ACTH fragment. ACTH (6-24) (human) is a competitive inhibitor of steroidogenesis induced by ACTH (1-39) and ACTH (5-24) (Kd:13.4 and 3.4 nM). ACTH (6-24) (human) inhibits corticosterone production and cAMP accumulation induced by hPTH 1-34[1][2].References
[1] Rafferty B, et al. Corticosteroidogenesis and adenosine 3', 5'- monophosphate production by the amino-terminal (1-34) fragment of human parathyroid hormone in rat adrenocortical cells. Endocrinology. 1983 Sep;113(3):1036-42. DOI:10.1210/endo-113-3-1036[2] Bristow AF, et al. Effects of ACTH (corticotropin) analogues on steroidogenesis and cyclic AMP in rat adrenocortical cells. Evidence for two different steroidogenically responsive receptors. Biochem J. 1980 Feb 15;186(2):599-603. DOI:10.1042/bj1860599
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33512-65-1(Acth (6-24)) Related Search
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