ChemicalBook > CAS DataBase List > inophyllum B
inophyllum B
inophyllum B
- CAS No.41135-06-2
- Chemical Name:inophyllum B
- CBNumber:CB01336023
- Molecular Formula:C25H24O5
- Formula Weight:404.46
- MOL File:41135-06-2.mol
inophyllum B Property
- Melting point 58-62 °C
- Boiling point 564.7±50.0 °C(Predicted)
- Density 1.249±0.06 g/cm3(Predicted)
- pka 13.37±0.70(Predicted)
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
inophyllum B Chemical Properties,Usage,Production
- Uses Inophyllum B ((+)-Inophyllum B) is a potent HIV Reverse Transcriptase inhibitor with an IC50 value of 38 nM. Inophyllum B inhibits HIV-1 (IC50=1.4 μM) in vitro cell culture. Inophyllum B can be isolated from the acetone extract of the giant African snail, Achatina fulica[1].
- IC 50 HIV-1: 1.4 μM (IC50); Reverse Transcriptase: 38 nM (IC50)
- References [1] Patil AD, et al. The inophyllums, novel inhibitors of HIV-1 reverse transcriptase isolated from the Malaysian tree, Calophyllum inophyllum Linn. J Med Chem. 1993 Dec 24;36(26):4131-8. DOI:10.1021/jm00078a001
inophyllum B Preparation Products And Raw materials
Raw materials
Preparation Products
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