Description
Boc-Glu-OBzl is an amino acid building block. It has been used in the synthesis of peptide-based inhibitors of human caspases and human rhinovirus (HRV) 3C protease that have enzyme inhibitory activity
in vitro.
Chemical Properties
White Solid
Uses
N-Boc-L-glutamic Acid α-Benzyl Ester is an effective substrate for vitamin K-dependent carboxylase. N-Boc-L-glutamic Acid α-Benzyl Ester is a monopeptide used to study the interaction of nucleic acid bases with peptides.
Uses
Boc-L-Glutamic acid 1-benzyl ester is an effective substrate for vitamin K-dependent carboxylase,it is a monopeptide used to study the interaction of nucleic acid bases with peptides.
reaction suitability
reaction type: Boc solid-phase peptide synthesis
References
[1] M GARCIA-CALVO. Inhibition of human caspases by peptide-based and macromolecular inhibitors.[J]. The Journal of Biological Chemistry, 1998, 273 49: 32608-32613. DOI:
10.1074/jbc.273.49.32608[2] PETER S. DRAGOVICH. Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide StructureActivity Studies[J]. Journal of Medicinal Chemistry, 1998, 41 15: 2819-2834. DOI:
10.1021/jm9800696
