ChemicalBook > CAS DataBase List > 6-ANILINO-5,8-QUINOLINEDIONE
6-ANILINO-5,8-QUINOLINEDIONE
6-ANILINO-5,8-QUINOLINEDIONE
- CAS No.91300-60-6
- Chemical Name:6-ANILINO-5,8-QUINOLINEDIONE
- CBNumber:CB0130280
- Molecular Formula:C15H10N2O2
- Formula Weight:250.25
- MOL File:91300-60-6.mol
6-ANILINO-5,8-QUINOLINEDIONE Property
- Melting point 184-185°C
- Boiling point 446.9±45.0 °C(Predicted)
- Density 1.400±0.06 g/cm3(Predicted)
- storage temp. 2-8°C
- solubility 0.1 M HCl: 1 mg/mL
- form solid
- pka -0.63±0.20(Predicted)
- color violet
- CAS DataBase Reference 91300-60-6(CAS DataBase Reference)
- FDA UNII TD9FS56333
- UNSPSC Code 41106305
- NACRES NA.77
Safety
- Hazard Codes :Xn,Xi
- Risk Statements :40-36/37/38
- Safety Statements :36/37-36-26
- WGK Germany :2
- HS Code :2933499090
-
NFPA 704:
0 2 0
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H315-H319-H335
- Precautionary statements P261-P280-P271
6-ANILINO-5,8-QUINOLINEDIONE Price
More Price(1)
- Brand: Sigma-Aldrich(India)
- Product number: A6563
- Product name : 6-Anilinoquinoline-5,8-quinone
- Purity: ≥95% (TLC), solid
- Packaging: 5MG
- Price: ₹16529.78
- Updated: 2022/06/14
- Buy: Buy
6-ANILINO-5,8-QUINOLINEDIONE Chemical Properties,Usage,Production
- Chemical Properties Red-Brown Solid
- Uses Inhibits nitric-oxide-induced activation of soluble guanylate cyclase (IC50=2μM) in a dose-dependent and reversible manner. It blocks acetylcholine induced vasorelaxation. Also an inhibitor of antigen-induced leukotriene release.
- Uses Inhibits nitric-oxide-induced activation of soluble guanylate cyclase (IC50=2) in a dose-dependent and reversible manner. It blocks acetylcholine induced vasorelaxation. Also an inhibitor of antigen-induced leukotriene release
- Uses LY83583 is an inhibitor of soluble guanylate cyclase and of cGMP production. It inhibits soluble guanylate cyclase in human platelets with an IC50 value of 2 μM. LY83583 also inhibits leukotriene synthesis in guinea pig lung and rat peritoneal cells with an IC50 value of 1.8 μM and is a noncompetitive inhibitor of glutathione reductase in bovine intestinal mucosa with a Ki value of 3 μM.[Cayman Chemical]
- Definition ChEBI: A quinolone that is quinoline-5,8-dione in which the hydrogen at position 6 is replaced by an anilino group.
-
Biological Activity
Primary Target
soluble guanylate cyclase', 'Target IC50: 2 μM against soluble guanylate cyclase
6-ANILINO-5,8-QUINOLINEDIONE Preparation Products And Raw materials
Raw materials
Preparation Products
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91300-60-6, 6-ANILINO-5,8-QUINOLINEDIONERelated Search:
- 4'-Hydroxyacetophenone BAY 41-2272 GUANYLIN (HUMAN) ODQ TYRPHOSTIN AG 1288 YC-1 GUANYLIN (RAT) Protoporphyrin IX L-Carnosine NS-2028 6-ANILINO-5,8-QUINOLINEDIONE 1-PHENYL-N-(PYRIDIN-3-YLMETHYL)METHYLAMINE 3-Pyridineethaneamine (2-PYRIDIN-3-YLETHYL)METHYLAMINE Ethanone, 1-(3-methyl-2-pyridinyl)- (9CI) 3-(2-PYRIDYL)-1-PROPENE 5,8-QUINOLINEQUINONE
- Heterocycles
- Aromatics
- Nitric Oxide Reagents
- Inhibitors
- All Inhibitors
- 抑制剂
- 生化试剂
- G Proteins and Cyclic Nucleotides
- Guanylyl Cyclase Inhibitors
- Cyclic Nucleotide Metabolism
- BioChemical
- Cell Signaling and Neuroscience
- Cell Biology
- 化合物LY83583,10 MM DMSO 溶液
- LY83583,SOLUBLE GUANYLATE CYCLASE抑制剂
- 化合物LY83583
- 6-苯胺基-5,8-喹啉二酮
- 4-苯胺-1-羟基苯
- 91300-60-6
- LY83583, 10 mM in DMSO
- LY83583, Soluble guanylate cyclase inhibitor
- 5,8-Quinolinedione, 6-(phenylamino)-
- LY-83583 (LY83583)
- (4-methyl-2-oxo-1-benzopyran-7-yl)oxy-phenylphosphinic acid
- LY 83583 - CAS 91300-60-6 - Calbiochem
- 6-ANILINO-5,8-QUINOLINEQUINONE
- 6-ANILINO-5,8-QUINOLINEDIONE
- 6-(PHENYLAMINO)-5,8-QUINOLINEDIONE
- LY 83583
- 5,8-Dihydro-5,8-dioxo-6-(phenylamino)quinoline, [(5,8-Dihydro-5,8-dioxoquinolin-6-yl)amino]benzene, 6-Anilinoquinoline-5,8-dione
- 5,8-Dihydro-5,8-dioxo-6-(phenylaMino)quinoline
- 6-(phenylamino)quinoline-5,8-dione
- 6-(anilino)quinoline-5,8-dione
- 6-(Phenylamino)-5,8-quinolinedione, LY-83,583
- 6-ANILINOQUINOLINE-5,8-QUINONE