Uses
Mannomustine dihydrochloride is an alkylating agent with antineoplastic activity. Mannomustine dihydrochloride causes severe bone marrow depression. Mannomustine dihydrochloride is a powerful vesicant.
Definition
ChEBI: Mannomustine dihydrochloride is an organic molecular entity.
Safety Profile
Poison by intravenous,
subcutaneous, and parented routes.
Experimental reproductive effects.
Questionable carcinogen with experimental
carcinogenic and neoplastigenic data. Human mutation data reported. A drug used
for the treatment of malignant neoplasms.
When heated to decomposition it emits very
toxic fumes of HCl and NOx. See also
MANNOMUSTINE.
References
[1] Some effects of 1-methyl-2-p-(isopropyl-carbamoyl)-benzyl-hydrazine and mannomustine on the metabolism of human erythrocytes in vitro
