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Euphorbiasteroid

Euphorbiasteroid Structure
Euphorbiasteroid
  • CAS No.28649-59-4
  • Chemical Name:Euphorbiasteroid
  • CBNumber:CB01118210
  • Molecular Formula:C32H40O8
  • Formula Weight:552.66
  • MOL File:28649-59-4.mol
Euphorbiasteroid Property
  • Melting point 199～200℃
  • Boiling point 633.1±55.0 °C(Predicted)
  • Density 1.23
  • storage temp. 4°C, protect from light
  • solubility DMSO:15.0(Max Conc. mg/mL);27.14(Max Conc. mM)
    DMF:5.0(Max Conc. mg/mL);9.05(Max Conc. mM)
  • form A crystalline solid
  • UNSPSC Code 41116107
  • NACRES NA.24
Safety
  • Safety Statements  :24/25
  • HS Code  :29061990
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Euphorbiasteroid Chemical Properties,Usage,Production

  • Uses Euphorbiasteroid is a compound used to induce HL-60 cells to apoptosis via promoting Bcl/Bax apoptotic signaling pathway in a dose-dependent manner.
  • Biological Functions Euphorbiasteroid, Euphorbia Factor L1 (EFL1) to be specific, with a tricyclic terpenoid skeleton, consisting of fused five-, eleven- and three-membered rings, is a diterpenoid isolated from the seeds of Euhporbia lathyris L. It is reported EFL1 could be helpful to reduces the expression of Bcl-2, PI3K, AKT and mTOR protein and mRNA, upregulates cleaved caspase-9 and caspase-3 levels, but shows no effect on pro-caspase-9 and pro-caspase-3. EFL1 also could induce apoptosis, and possess anticancer, antiadipogenesis, antiosteoclastogenesis and multi-drug resistance-modulating effect.
    Euphorbiasteroid showed effects on adipogenesis of 3T3-L1 pre-adipocytes. Euphorbiasteroid also has the potential to reverse P-glycoprotein (P-gp)-mediated multi-drug resistance (MDR) by using the drug-sensitive human sarcoma cell line MES-SA and its MDR counterpart MES-SA/Dx5.EFL1 inhibited osteoclastogenesis and induced osteoclast apoptosis. Euphorbiasteroid suppressed osteoclast formation and bone resorption at both initial and terminal differentiation stages.
Euphorbiasteroid Preparation Products And Raw materials
Raw materials
Preparation Products
Euphorbiasteroid Suppliers
Global(141)Suppliers
  • Supplier：
    career henan chemical co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：sales@coreychem.com
  • Country：China
  • ProdList：29858
  • Advantage：58

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Euphorbiasteroid Spectrum
28649-59-4, EuphorbiasteroidRelated Search:
  • 萜类
  • 抑制剂
  • 试剂
  • 药靶配体
  • 有机化合物
  • 标准品，对照品
  • 标准品 -中药标准品
  • 对照品-中药对照品
  • 标准品-对照品
  • 分析试剂标准品
  • 中药对照品
  • 对照品
  • 标准品
  • 植物提取物
  • C32H40O8
  • 32H40O8
  • (1AR,4AR,6S,7S,7AR,8S,9R,11AS,E)-1,1,3,6-四甲基-4-氧代-7-(2-苯基乙酰氧基)-1,1A,4,6,7,7A,8,10,11,11A-十氢螺[环戊并[A]环丙并[F][11]轮烯-9,2'-环氧乙烷]-4A,8(5H)-二基 二乙酸酯
  • 千金子甾醇,10 MM DMSO 溶液
  • (1AR,4AR,6S,7S,7AR,8S,9R,11AS,E)-1,1,3,6-四甲基-4-氧代-7-(2-苯基乙酰氧基)-1,1A,4,6,7,7A,8,10,11,11A-十氢螺[环戊并[A]环丙并[F][11]轮烯-9,2'-环氧乙烷]-4A,8(5H)-二基 二乙酸酯
  • 标准品对照品】EUPHOBIASTEROID
  • 千金子甾醇(千金子素L1)(标定对照品)
  • 续随二萜酯
  • 千金子甾醇对照品
  • 千金子甾醇(分析标准品)
  • E千金子甾醇 标准品
  • 千金子甾醇标准品
  • 千金子甾醇, 来源于千金子
  • 千金子甾醇,千金子素L1
  • EUPHOBIASTEROID 千金子甾醇(≥95%)
  • 千金子甾醇(95%)
  • 千金子素L1
  • 28649-59-4
  • Euphorbiasteroid, 10 mM in DMSO
  • (1aR,4aR,6S,7S,7aR,8S,9R,11aS,E)-1,1,3,6-Tetramethyl-4-oxo-7-(2-phenylacetoxy)-1,1a,4,6,7,7a,8,10,11,11a-decahydrospiro[cyclopenta[a]cyclopropa[f][11]annulene-9,2'-oxiran]-4a,8(5H)-diyl diacetate
  • Euphorbiasteroid（EuphorbiaFactor L1）
  • (1aS,2E,4aR,6S,7S,7aS,8S,9R,11aS)-4a,8-bis(acetyloxy)-1,1,3,...
  • (1aS,2E,4aR,6S,7S,7aS,8S,9R,11aS)-4a,8-bis(acetyloxy)-1,1,3,6-tetramethyl-4-oxo-1,1a,4,4a,5,6,7,7a,8,10,11,11a-dodecahydrospiro[cyclopenta[a]cyclopropa[f][11]annulene-9,2'-oxiran]-7-yl phenylacetate
  • Euphorbiasteroid, 98%, from Leptochloa chinensis (L.) Nees
  • Euphorbia factor L1
  • Benzeneacetic acid 4a,8-bis(acetyloxy)-1,1a,4,4a,5,6,7,7a,8,10,11,11a-dodecahydro-1,1,3,6-tetramethyl-4-oxospiro[9H-cyclopenta[a]cyclopropa[f]cycloundecene-9,2'-oxiran]-7-yl ester
  • Benzeneacetic acid (1aR,2'R,2E,4aR,6S,7S,7aR,8S,11aS)-4a,8-bis(acetyloxy)-1,1a,4,4a,5,6,7,7a,8,10,11,11a-dodecahydro-1,1,3,6-tetramethyl-4-oxospiro[9H-cyclopenta[a]cyclopropa[f]cycloundecene-9,2'-oxiran]-7-yl ester
  • 6,20-Epoxylathyrol phenylacetate diacetate
  • Daughter son sterol

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