Minalrestat

Minalrestat Structure
Minalrestat
  • CAS No.129688-50-2
  • Chemical Name:Minalrestat
  • CBNumber:CB01117314
  • Molecular Formula:C19H11BrF2N2O4
  • Formula Weight:449.206
  • MOL File:129688-50-2.mol
Minalrestat Property
  • Melting point 231-232℃
  • Density 1.45
  • FDA UNII G44PE6QB31
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Minalrestat Chemical Properties,Usage,Production

  • Uses Inhibitor(aldose reductase).
  • Definition ChEBI: Minalrestat is a member of isoquinolines.
  • in vivo

    Minalrestat (Oral gavage, 10 mg/kg/day, for 30 days) corrects the decreased microvascular reactivity in diabetic rats[1].
    Minalrestat (Oral gavage, 10 mg/kg) restores the reduced number of leukocytes adhered and migrated leukocytes in postcapillary venules in diabetic rats[2].

    Animal Model:Alloxan (40 mg/kg i.v.)-induced diabetic rats[1]
    Dosage:10 mg/kg/day
    Administration:Oral gavage, for 30 days.
    Result:Restored the decreased microvascular reactivity.
Minalrestat Preparation Products And Raw materials
Raw materials
Preparation Products
Minalrestat Suppliers
Global(16)Suppliers
  • Supplier：
    Alchem Pharmtech,Inc.
  • Tel：8485655694
  • Email：sales@alchempharmtech.com
  • Country：United States
  • ProdList：63687
  • Advantage：58
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
  • Country：United States
  • ProdList：32159
  • Advantage：58
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：
  • Email：support@targetmol.com
  • Country：United States
  • ProdList：38630
  • Advantage：58
  • Supplier： TargetMol Chemicals Inc.
  • Tel： 15002134094
  • Email：marketing@targetmol.cn
  • Country：China
  • ProdList：19727
  • Advantage：58
Minalrestat Spectrum
129688-50-2, MinalrestatRelated Search:
  • 抑制剂
  • C19H11BrF2N2O4
  • 化合物 T33389
  • 米那司他
  • 129688-50-2
  • WAYARI-509
  • WAY-ARI-509
  • ARI-509
  • ARI509
  • Spiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrone, 2-[(4-bromo-2-fluorophenyl)methyl]-6-fluoro-
  • 2-(4-Bromo-2-fluorobenzyl)-6-fluoro-1H-spiro[isoquinoline-4,3'-pyrrolidine]-1,2',3,5'(2H)-tetraone
  • Minalrestat
  • Unii-G44pe6qb31

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