Originator
Thiodrol,Shionogi,Japan,1977
Uses
An anabolic steroid that exhibits androgenic, myogenic, anabolic, anticatabolic, progestational, deciduomatogenic, and antiestrogenic activities. An anti-estrogen with anti-mammry cancer agent.
Definition
ChEBI: Epitiostanol is an organic molecular entity.
Manufacturing Process
A solution of 2β-thiocyanato-3α-methanesulfonyloxy-5α-androstan-17β-ol 17-
acetate (0.82 part by weight) and potassium hydroxide (0.9 part by weight) in
diglyme (20 parts by volume) is refluxed on a water bath for 24 hours while
stirring. To the reaction mixture, there is added water, and the separated
substance is collected by filtration and crystallized from hexane to give 2β,3β-
epithio-5α-androstan-17β-ol (0.60 part by weight) as crystals melting at
132.5°C to 134°C.
Therapeutic Function
Antineoplastic
