Chemical Properties
WHITE TO ALMOST WHITE CRYSTALS OR CRYST. POWDER
Uses
Phenylarsine oxide is used as a poultry coccidiostat in veterinary medicine. It is also used in a membrane-permeable protein tyrosine phosphatase inhibitor.
Definition
ChEBI: An arsine oxide derived from phenylarsine.
General Description
Phenylarsine oxide (PhAsO
4) is a bifunctional SH group chemical. It is hydrophobic in nature.
Biochem/physiol Actions
Phenylarsine oxide?(PAO) can reduce the motility and sustainability of Setaria cervi. It has the ability to stimulate cyclosporin A-sensitive transition in the presence of EGTA (ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid). It acts as a stimulator of mitochondrial ion fluxes.
Safety Profile
Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits toxic fumes of As. See also ARSENIC COMPOUNDS
