Panobacumab
- Product NamePanobacumab
- CAS885053-97-4
- CBNumberCB98080784
- MW0
- MOL FileMol file
- MSDS FileSDS
Panobacumab Price
| Product number | Packaging | Price | Product description | Buy |
|---|---|---|---|---|
| ChemScene CS-0612950 | 1mg | $282 | Panobacumab 98.24% |
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| ChemScene CS-0612950 | 5mg | $737 | Panobacumab 98.24% |
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| ChemScene CS-0612950 | 10mg | $1170 | Panobacumab 98.24% |
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| ApexBio Technology BA1454 | 1mg | $234 | Panobacumab |
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| ApexBio Technology BA1454 | 5mg | $612 | Panobacumab |
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Panobacumab Chemical Properties,Usage,Production
Uses
Panobacumab (KBPA101) is a fully human IgM/κ monoclonal antibody generated by immortalizing human B lymphocytes against the LPS O polysaccharide of serotype O11 of P. aeruginosa[1].in vivo
Panobacumab (KBPA101) (1-4 mg/kg; i.v.; once) protects mice from systemic infection with P. aeruginosa serotype O11 in a murine burn wound model[1].
Panobacumab (KBPA101) (0.005-0.4 mg/kg; i.v.; once) protects mice from local lung infection with P. aeruginosa serotype O11 in an acute lung infection model[1].
| Animal Model: | Female NMRI mice, murine burn wound model[1] |
| Dosage: | 1, 2, or 4 mg/kg |
| Administration: | Intravenous injection, single dose |
| Result: | Significantly reduced mortality compared to untreated control animals administered either immediately or 4 h postchallenge. |
| Animal Model: | BALB/c mice, acute lung infection model[1] |
| Dosage: | 0.005 to 0.4 mg/kg |
| Administration: | Intravenous injection, single dose |
| Result: | Led to rapid clearance of P. aeruginosa from the lung, completely cleared systemic P. aeruginosa from the spleen, whereas live bacteria were still present in untreated mice at 48 h postchallenge, showed milder macroscopic lung pathology at 6 and 24 h after infection. |
References
[1] Horn MP, et al. Preclinical in vitro and in vivo characterization of the fully human monoclonal IgM antibody KBPA101 specific for Pseudomonas aeruginosa serotype IATS-O11. Antimicrob Agents Chemother. 2010 Jun;54(6):2338-44. DOI:10.1128/AAC.01142-09Preparation Products And Raw materials
Panobacumab Suppliers
Global(18)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 1-631-485-4226; 16314854226 |
info@bocsci.com | United States | 9920 | 65 | |
| 177-54423994 17754423994 |
2853530910@QQ.com | China | 7996 | 62 | |
| 15817493340 | 981810490@qq.com | China | 1577 | 58 | |
| 027-65317797 15926423062 |
422450190@qq.com | China | 10302 | 58 | |
| 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 | |
| 027-65279366 18108604356 |
products@biolabreagent.com | China | 9864 | 58 | |
| 13720134139 086-15871494362 13720134139 |
orders@jknbiochem.com | China | 7284 | 58 | |
| 021-65675885 18964387627 |
customer_service@efebio.com | China | 11963 | 58 | |
| 027-027-16602739303 16602739303 |
673003916@qq.com | China | 4622 | 58 | |
| 15111215862 18229892877 |
3062105966@qq.com | China | 5571 | 58 |
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