Bococizumab
- Product NameBococizumab
- CAS1407495-02-6
- CBNumberCB68080899
- MW0
- MOL FileMol file
- MSDS FileSDS
Bococizumab Price
| Product number | Packaging | Price | Product description | Buy |
|---|---|---|---|---|
| ChemScene CS-0612900 | 1mg | $455 | Bococizumab 99.80% |
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| ChemScene CS-0612900 | 5mg | $1137 | Bococizumab 99.80% |
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| ChemScene CS-0612900 | 10mg | $1820 | Bococizumab 99.80% |
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| ChemScene CS-0612900 | 25mg | $3196 | Bococizumab 99.80% |
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| aablocks AA029Z48 | 1mg | $298 | Bococizumab |
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Bococizumab Chemical Properties,Usage,Production
Uses
Bococizumab (PF-04950615) is an anti-human PCSK9 inhibitory antibody that reduces LDL cholesterol levels. Bococizumab can be used in the research of hypercholesterolemia[1][2].in vivo
Bococizumab (0-100 mg/kg, i.v.) decreases maternal and fetal cholesterol and does not affect rat embryo-fetal development[2].
| Animal Model: | Pregnant Sprague-Dawley (SD) rats[1] |
| Dosage: | 0, 10, 30, and 100 mg/kg |
| Administration: | Intravenous injection (i.v.) |
| Result: | Decreased in fetal cholesterol levels. Showed well tolerance and no effects on ovarian or uterine parameters. |
References
[1] Koutaro Yokote, et al. Efficacy and Safety of Bococizumab (RN316/PF-04950615), a Monoclonal Antibody Against Proprotein Convertase Subtilisin/Kexin Type 9, in Hypercholesterolemic Japanese Subjects Receiving a Stable Dose of Atorvastatin or Treatment-Naive - Results From a Randomized, Placebo-Controlled, Dose-Ranging Study. Circ J. 2017 Sep 25;81(10):1496-1505. DOI:10.1253/circj.CJ-16-1310[2] Sarah N Campion, et al. Decreased maternal and fetal cholesterol following maternal bococizumab (anti-PCSK9 monoclonal antibody) administration does not affect rat embryo-fetal development. Regul Toxicol Pharmacol. 2015 Nov;73(2):562-70. DOI:10.1016/j.yrtph.2015.08.007
Preparation Products And Raw materials
Bococizumab Suppliers
Global(28)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 15026964105 | 2881489226@qq.com | China | 87240 | 60 | |
| 177-54423994 17754423994 |
2853530910@QQ.com | China | 7996 | 62 | |
| +1-781-999-5354; +1-00000000000 |
marketing@targetmol.com | United States | 32431 | 58 | |
| 021-58447131 13564518121 |
doncunbiosci@gmail.com | China | 618 | 58 | |
| +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 | |
| 15817493340 | 981810490@qq.com | China | 1577 | 58 | |
| 027-65317797 15926423062 |
422450190@qq.com | China | 10302 | 58 | |
| 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 | |
| 4008200310 15002144251 |
marketing@tsbiochem.com | China | 24951 | 58 | |
| 027-65279366 18108604356 |
products@biolabreagent.com | China | 9864 | 58 |
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