L-PHENYLALANINE DEHYDROGENASE

Uses

L-Phenylalanine dehydrogenase is a NAD+-dependent oxidoreductase that catalyzes the reversible, oxidative deamination of L-phenylalanine which results in its degradation. L-Phenylalanine dehydrogenase is used to study phenylalanine metabolism and phenylalanine, tyrosine and tryptophan biosynthesis.

Biochem/physiol Actions

Phenylalanine dehydrogenase (PheDH) is considered as an effective enzyme to estimate the quantity of phenylalanine to distinguish phenylketonuria (PKU) disease.