Factor H, Human Factor H, Human, is a single-chain multi-functional glycoprotein that regulates formation and function of complement C3 and C5 convertase enzymes.
FACTOR H, HUMAN Chemical Properties,Usage,Production
Uses
Complement factor H (CFH) is a plasma regulator of the complement protein C3b in the alternative pathway of the complement system. Research has shown that binding of CFH is important for pathogenesis of group A streptococcus (GAS), and inhibition of this binding may be an effective management of GAS infections.
Biochem/physiol Actions
Complement factor H plays an essential role in the homeostasis of the complement system and in preventing collateral damage to bystander cells and tissues by complement activation.
