Chemical Properties
white to light beige crystalline powder, crystals
Uses
p-Toluidine Hydrochloride acts as a reagent for the preparation and biological activity of N-acylleucine (arylaminoethyl)amides as non-covalent inhibitors of cathepsin K, L and S. Catalyst in the chemistry of azasteroids.
General Description
Off-white to grayish-white crystals.
Air & Water Reactions
Water soluble. May be sensitive to moisture.
Reactivity Profile
4-Methylaniline hydrochloride reacts with oxidizing and alkali materials. .
Fire Hazard
Flash point data for 4-Methylaniline hydrochloride are not available, but 4-Methylaniline hydrochloride is probably combustible.
Safety Profile
Poison by
intraperitoneal route. Moderately toxic by
ingestion. Questionable carcinogen with
experimental carcinogenic and tumorigenic
data. When heated to decomposition it
emits very toxic fumes of NOx and HCl. See
also p-TOLUIDINE.
Purification Methods
Crystallise the salt from MeOH containing a few drops of conc HCl or aqueous EtOH. Dry it under vacuum over paraffin chips. [Beilstein 12 II 587, 12 III 2021, 12 IV 1869.]
