Synthesis
General procedure for the synthesis of 6-fluoro-4-hydroxyquinazoline from 2-amino-5-fluorobenzoic acid and the compound (CAS: 77287-34-4): operate with reference to the reaction and post-processing of Example 5, substituting only the type of o-aminobenzoic acid derivative. The specific experimental results are detailed in Table 4.
References
[1] Patent: EP1997812, 2008, A1. Location in patent: Page/Page column 8
[2] European Journal of Medicinal Chemistry, 2012, vol. 50, p. 264 - 273
[3] Molecules, 2006, vol. 11, # 6, p. 383 - 392
[4] Bioorganic and Medicinal Chemistry, 2007, vol. 15, # 11, p. 3768 - 3774
[5] Chemistry and Biodiversity, 2018, vol. 15, # 6,
