Description
Phencyclidine hydrochloride (PCP) is a psychoactive drug that has inhibitory, excitatory, analgesic and hallucinogenic effects on the central nervous system. Its chemical name is 1-(1-phenylcyclohexane)piperidine. It is a dissociative drug once used by anesthesiologists as an anesthetic with hallucinogenic and neurotoxic effects.
Chemical Properties
Crystalline Solid
Uses
Controlled substance (depressant). Anesthetic (intravenous).
Uses
Anesthetic (intravenous).
Controlled substance (depressant).
brand name
Sernylan (Parke-Davis).
Biological Activity
Non-competitive NMDA receptor antagonist and sigma receptor agonist. Psychostimulant; induces rotational behavior, head-weaving and cognitive dysfunction in rats.
Biochem/physiol Actions
σ opioid receptor agonist and psychostimulant; inhibits NMDA glutamate receptor activation by binding to an allosteric site within the ion channel.
Safety Profile
Poison by ingestion,subcutaneous, intravenous, and intraperitoneal routes.Human systemic effects by ingestion and intravenousroutes: distorted perceptions, euphoria, excitement,hallucinations, and paresthesia. An experimental teratogen.Other experime
