Uses
5-Fluoro-2′-deoxyuridine 5′-monophosphate (FdUMP) is used extensively in studies on the activity and function of thymidylate synthase (TS).
Uses
5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt has been used as an anti-mitotic agent and is used extensively in studies on the activity and function of thymidylate synthase (TS).
Uses
5-Fluoro-2’deoxyuridine 5’Monophosphate is used in the preparation of diaminomitosene nucleotide derivatives with anti-neoplastic activity.
Biochem/physiol Actions
5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt (FdUMP) is an DNA synthesis inhibitor. FdUMP along with RNA synthesis inhibitor 3′-C-ethinylcytidine induces cell death in cervical cancer cells at nanomolar concentrations.
