Uses
Formaldehyde Dehydrogenase from
Pseudomonas sp. has been used in standard curve generation for the demethylation-FDH assay of lysine specific demethylase 1 (LSD1) and in formaldehyde dehydrogenase (FDH) assay.
General Description
Formaldehyde Dehydrogenase (FDH) belongs to the medium-chain alcohol dehydrogenase family. It is encoded by the fdhA and fdhB gene in
Pseudomonas aeruginosa. The FDH sequences of
P. aeruginosa and
P. putida are conserved and show homology. FDH exists as dimer and tetramer with zinc in their catalytic active site. The monomer corresponds to 350-400 amino-acid residues.
Biochem/physiol Actions
Formaldehyde dehydrogenase catalyzes the conversion of formaldehyde to formate.
