Description
Azido-PEG8-azide is a aqueous soluble, homebifunctional PEG reagent The azide (N3) group cis very reactive with alkyne, such as BCN, DBCO via Click Chemistry to yield a stable triazole moiety
Uses
Azido-PEG8-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG8-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
