Description References
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Indirubin

Description References
Indirubin Structure
Indirubin
  • CAS No.479-41-4
  • Chemical Name:Indirubin
  • CBNumber:CB9296505
  • Molecular Formula:C16H10N2O2
  • Formula Weight:262.26
  • MOL File:479-41-4.mol
Indirubin Property
  • Melting point: :350°C(lit.)
  • Boiling point: :496.6±45.0 °C(Predicted)
  • Density  :1.417±0.06 g/cm3(Predicted)
  • storage temp.  :-20°C
  • pka :9.13±0.20(Predicted)
  • form  :Purple powder.
  • λmax :540nm(DMSO)(lit.)
  • CAS DataBase Reference :479-41-4(CAS DataBase Reference)
Safety
  • RTECS  :DU2995000
  • HS Code  :29339900
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
Indirubin Price More Price(6)
  • Brand: Sigma-Aldrich
  • Product number: PHL89716
  • Product name : Indirubin
  • Purity:  phyproof? Reference Substance
  • Packaging: 10mg
  • Price: $316
  • Updated: 2019/12/02
  • Buy: Buy
  • Brand: TCI Chemical
  • Product number: I0868
  • Product name : Indirubin
  • Purity: >97.0%(HPLC)
  • Packaging: 25mg
  • Price: $250
  • Updated: 2019/12/02
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 14155
  • Product name : Indirubin
  • Purity: ≥98%
  • Packaging: 5mg
  • Price: $48
  • Updated: 2018/11/13
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 14155
  • Product name : Indirubin
  • Purity: ≥98%
  • Packaging: 10mg
  • Price: $91
  • Updated: 2018/11/13
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 14155
  • Product name : Indirubin
  • Purity: ≥98%
  • Packaging: 25mg
  • Price: $204
  • Updated: 2018/11/13
  • Buy: Buy

Indirubin Chemical Properties,Usage,Production

  • Description Indirubin is the active ingredient of Danggui Longhui Wan, a traditional Chinese medicine containing plants such as Indigofera tinctoria L. and Isatis tinctoria L, which are used in traditional Chinese medicine to treat chronic diseases. Indirubin and its analogues are reported as potent inhibitors of cyclin-dependent kinases (CDKs). This could attribute to the positive effect of indirubin on counteracting proliferative diseases, such as chronic myelocytic leukemia (CML), a slowly progressive disease characterized by the overproduction of granulocytes.
  • References [1] Tina Bla?evi?, Elke H. Heiss, Atanas G. Atanasov, Johannes M. Breuss, Verena M. Dirsch and Pavel Uhrin, Indirubin and Indirubin Derivatives for Counteracting Proliferative Diseases, Evidence-Based Complementary and Alternative Medicine, 2015, vol. 2015, Article ID 654098
    [2] Ralph Hoessel, Sophie Leclerc, Jane A. Endicott, Martin E. M. Nobel, Alison Lawrie, Paul Tunnah, Maryse Leost, Eve Damiens, Dominique Marie, Doris Marko, Ellen Niederberger, Weici Tang, Gerhard Eisenbrand and Laurent Meijer, Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases, Nature Cell Biology, 1999, vol. 1, 60-67
  • Uses Indigopurpurin is a purple 3,2-bisindole derivative and was shown to exhibit inhibitory allergic contact dermatitis via regulating T helper (Th)-mediated immune system in DNCB-induced model.
  • Uses An inhibitor of GSK-3β and cyclin-dependent kinases.
Indirubin Preparation Products And Raw materials
Raw materials
Preparation Products
Indirubin Suppliers
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  • Advantage:60
  • Supplier:
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479-41-4, IndirubinRelated Search:
  • Indirubin 479-41-4
  • Isoindogotin
  • (delta(sup2,3’)-biindoline)-2’,3-dione
  • 3-(1,3-dihydro-3-oxo-2h-indol-2-ylidene)-1,3-dihydro-2h-indol-2-on
  • c.i.73200
  • 2-(2-oxo-1h-indol-3-ylidene)-1h-indol-3-one
  • COUROUPITINE B
  • INDIGOPURPURIN
  • INDIGO RED
  • INDIRUBIN
  • CouroupitineB,IndigoRed,Indigopurpurin
  • 2H-Indol-2-one,3-(1,3-dihydro-3-oxo-2H-indol-
  • 2-ylidene)-1,3-dihydro-
  • Indirubin,Couroupitine B
  • C.I.75790
  • Δ2,3'(2'H,3H)-Bi[1H-indole]-2',3-dione
  • [.delta.2,3'-Biindoline]-2',3-dione
  • [2,3'-Biindolinylidene]-2',3-dione
  • Indirubin (Synthetic), >=98%
  • Indirubin/Folium Isatidis Extract
  • 2H-Indol-2-one, 3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-
  • Nsc105327
  • INDIRUBIN (RG)
  • (E)-3-(3-oxoindolin-2-ylidene)indolin-2-one
  • Indirubin, 98%, from Isatis tinctoria
  • 3-(1,3-dihydro-3-oxo-2h-indol-2-ylidene)-1,3-dihydro-
  • Indirubin (Synthetic)
  • 479-41-4
  • C16H10N2O2
  • Active Pharmaceutical Ingredients
  • Natural Plant Extract
  • Inhibitors