Delafloxacin meglumine
- Product NameDelafloxacin meglumine
- CAS352458-37-8
- CBNumberCB92666618
- MFC25H29ClF3N5O9
- MW635.98
- MDL NumberMFCD26142921
- MOL File352458-37-8.mol
- MSDS FileSDS
Chemical Properties
storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
solubility | Soluble in DMSO |
form | Powder |
color | Off-white to yellow |
InChIKey | AHJGUEMIZPMAMR-KUAVVOKVNA-N |
SMILES | [C@@H](O)([C@@H](O)CNC)[C@H](O)[C@H](O)CO.ClC1C(N2CC(O)C2)=C(F)C=C2C(=O)C(C(=O)O)=CN(C3N=C(N)C(F)=CC=3F)C=12 |&1:0,2,7,9,r| |
FDA UNII | N7V53U4U4T |
Delafloxacin meglumine Price
Product number | Packaging | Price | Product description | Buy |
---|---|---|---|---|
Cayman Chemical 27935 | 10mg | $62 | Delafloxacin (meglumine) |
Buy |
Cayman Chemical 27935 | 250mg | $1115 | Delafloxacin (meglumine) |
Buy |
Cayman Chemical 27935 | 50mg | $270 | Delafloxacin (meglumine) |
Buy |
Cayman Chemical 27935 | 100mg | $507 | Delafloxacin (meglumine) |
Buy |
ApexBio Technology A3357 | 100mg | $551 | Delafloxacinmeglumine |
Buy |
Delafloxacin meglumine Chemical Properties,Usage,Production
Physical Form
SolidDescription
Delafloxacin meglumine (Baxdela, WQ-3034, ABT-492, RX-3341; Melinta Therapeutics) was approved by the U.S. Food and Drug Administration (FDA) in June 2017 for the treatment of acute bacterial skin and skin structure infections on the basis of data from two phase III trials.Uses
Delafloxacin is a broad-spectrum anionic fluoroquinolone and its distinct chemical structure increases its potency in acidic environments. It is known to inhibit DNA replication and repair by targeting DNA gyrase and topoisomerase IV. Delafloxacin is administered via both oral and parenteral routes. It has potent activity against methicillin-resistant Staphylococcus aureus and Streptococci, and is also effective against Enterobacteriaceae and Pseudomonas aeruginosa.Indications
Delafloxacin meglumine (Baxdelae Melinta) is a fluoroquinolone antibacterial agent with properties that are most similar to other members of this class, such as levofloxacin, moxifloxacin, and ciprofloxacin. It is supplied in formulations for oral and intravenous administration. It is indicated for the treatment of adults with ABSSSIs caused by susceptible isolates of the gram-positive bacteria Staphylococcus aureus (including methicillin-resistant [MRSA] and methicillin-susceptible isolates), Staphylococcus haemolyticus, Staphylococcus lugdunensis, Streptococcus agalactiae, Streptococcus anginosus group (including S. anginosus, S. intermedius, and S. constellatus), Streptococcus pyogenes, and Enterococcus faecalis, and the gram-negative bacteria Escherichia coli, Enterobacter cloacae, Klebsiella pneumoniae, and Pseudomonas aeruginosa. It is the first fluoroquinolone to be demonstrated to be effective in the treatment of infections caused by MRSA, and its spectrum of antibacterial action, which also includes problem pathogens such as Pseudomonas aeruginosa, is broader than that of other antimicrobial agents that are indicated for the treatment of ABSSSIs[1].Biological Activity
Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine is a broad spectrum fluoroquinolone antibiotic. Delafloxacin has a wide range of activity against drug-resistant Staphylococcus aureus, Streptococcus pneumoniae and Klebsiella pneumoniae.References
[1] Daniel A. Hussar, Molly A. Walter. “Delafloxacin meglumine, Meropenem trihydrate/vaborbactam, Secnidazole, and Benznidazole.” ACS Applied Bio Materials 58 2 (2018): Pages 223-227.Delafloxacin meglumine Supplier
Global(126)Suppliers
Supplier | Tel | Country | ProdList | Advantage | ||
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28-85305008 | CHINA | 964 | 58 | |||
+16313385890 | info@protheragen-ing.com | United States | 3868 | 58 | ||
+86-18600796368 +86-18600796368 |
sales@sjar-tech.com | China | 484 | 58 | ||
+undefined-21-51877795 | ivan@atkchemical.com | China | 32956 | 60 | ||
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+1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 | ||
+86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39894 | 58 | ||
13480692018 | ramyan@ex-biotech.com | CHINA | 954 | 58 | ||
+1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32161 | 58 | ||
+8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
352458-37-8, Delafloxacin meglumineRelated Search
- Deschloro Delafloxacin Ethyl Ester
- Delafloxacin Dimer Impurity 1
- Benzenepropanoic acid, α-[[(6-amino-3,5-difluoro-2-pyridinyl)amino]methylene]-3-chloro-2,4,5-trifluoro-β-oxo-, ethyl ester
- NA
- Delafloxacin Ethyl Ester
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