Chemical Properties
White to off-white crystalline powder
Uses
Fmoc-β-azido-Ala-OH chloride is a general
N-terminal protected reagent used in the solid phase peptide synthesis. Azido group allows it to undergo copper-mediated click chemistry reactions.
It can be used in:
- Synthesis of α-N-acetylgalactosamine (α-GalNAc) linked antifreeze glycopeptides (AFGPs).
- Synthesis of stimuli-responsive multifunctional peptide gatekeepers for drug delivery applications.
- Synthesis of triazole-linked glycopeptides via Cu(I)-catalyzed 1,3-dipolar cycloaddition (CuAAC).
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
reaction type: click chemistry